SCHEMBL7121816

SCHEMBL7121816

Cc1ccc(CC(=O)N2CCN(C(=O)Cc3ccc(C)cc3)CC2)cc1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.78
KMT2A Q03164 2/20 0.78
SMN1; SMN2 Q16637 4/20 0.71
LMNA P02545 1/20 0.71
ALDH1A1 P00352 3/20 0.68
GFER P55789 1/20 0.66
KDM4E B2RXH2 1/20 0.64
CYP2C19 P33261 2/20 0.63
HPGD P15428 2/20 0.63
POLB P06746 2/20 0.62
GPR183 P32249 1/20 0.61
GAA P10253 1/20 0.61
PKM P14618 1/20 0.61
MAPT P10636 1/20 0.58
CYP1A2 P05177 1/20 0.58
CYP3A4 P08684 1/20 0.58
CYP2D6 P10635 1/20 0.58
CYP2C9 P11712 1/20 0.58
NPSR1 Q6W5P4 1/20 0.58
HSD11B1 P28845 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10195746 0.93 MEN1 (0.69) MEN1KMT2ASMN1; SMN2LMNAALDH1A1
SCHEMBL14817922 0.93 MEN1 (0.69) MEN1KMT2ASMN1; SMN2LMNAALDH1A1
SCHEMBL17572089 0.92 MEN1 (0.69) MEN1KMT2ASMN1; SMN2LMNAALDH1A1
SCHEMBL17572094 0.92 MEN1 (0.69) MEN1KMT2ASMN1; SMN2LMNAALDH1A1
SCHEMBL12082384 0.91 SMN1; SMN2 (0.70) MEN1KMT2ASMN1; SMN2LMNAALDH1A1
SCHEMBL22663722 0.90 HSD11B1 (0.74) MEN1KMT2ASMN1; SMN2LMNAALDH1A1
SCHEMBL27253358 0.89 MEN1 (0.65) MEN1KMT2ASMN1; SMN2LMNAALDH1A1
SCHEMBL10174349 0.88 MAPT (0.68) MEN1KMT2ASMN1; SMN2LMNAALDH1A1
SCHEMBL14543057 0.86 ALDH1A1 (0.68) MEN1KMT2ASMN1; SMN2LMNAALDH1A1
SCHEMBL14817934 0.86 MEN1 (0.61) MEN1KMT2ASMN1; SMN2LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6527384-B2 Decolorizable ink composition and ink jet printer using the ink composition RICOH COMPANY, LTD. (JP) 2003-03-04 US claimed
EP-1149877-B1 Decolorizable ink composition and ink jet printer using the ink composition RICOH KK (JP) 2003-06-11 EP disclosed
US-6527384-B2 Decolorizable ink composition and ink jet printer using the ink composition RICOH COMPANY, LTD. (JP) 2003-03-04 US disclosed
US-20020175982-A1 Decolorizable ink composition and ink jet printer using the ink composition RICOH COMPANY, LTD. (JP) 2002-11-28 US disclosed
EP-1149877-A1 Decolorizable ink composition and ink jet printer using the ink composition Ricoh Company, Ltd. (JP) 2001-10-31 EP disclosed
US-4663641-A LEUCO DYES; DECOLORIZING AGENTS, PIPERAZINE COMPOUND; AMIDES AND TERTIARY AMINES RICOH COMPANY, LTD. (JP) 1987-05-05 US disclosed