Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 7/20 | 0.45 |
| ▸ | GSK3B | P49841 | 7/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.35 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5868283 | 0.80 | GSK3A (0.45) | GSK3AGSK3BGAAMAPK1SMN1; SMN2 | |
| SCHEMBL31580031 | 0.76 | GSK3B (0.55) | GSK3AGSK3BGAAMAPK1CYP3A4 | |
| SCHEMBL7712655 | 0.76 | GSK3A (0.45) | GSK3AGSK3BGAAMAPK1SMN1; SMN2 | |
| SCHEMBL19377760 | 0.72 | GSK3B (0.46) | GSK3AGSK3BGAAMAPK1SMN1; SMN2 | |
| SCHEMBL1722780 | 0.70 | GSK3B (0.71) | GSK3AGSK3BGAAMAPK1ALDH1A1 | |
| SCHEMBL3807230 | 0.68 | ALDH1A1 (0.41) | GSK3AGSK3BGAAMAPK1ALDH1A1 | |
| SCHEMBL6645924 | 0.68 | GSK3A (0.45) | GSK3AGSK3BGAAMAPK1SMN1; SMN2 | |
| SCHEMBL6226538 | 0.68 | SMN1; SMN2 (0.48) | GSK3AGSK3BGAASMN1; SMN2EP300 | |
| SCHEMBL24205248 | 0.65 | GSK3A (0.39) | GSK3AGSK3BSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL5306506 | 0.65 | MAPK1 (0.71) | GSK3AGSK3BGAAMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8252925-B2 | Method for the production of 3-phenyl(thio)uracils and dithiouracils | BASF AKTIENGESELLSCHAFT (DE) | 2012-08-28 | — | — | US | claimed |
| US-7737275-B2 | Method for producing 3-phenyl(thio)uracils and 3-phenyldithiouracils | BASF AKTIENGESELLSCHAFT (DE) | 2010-06-15 | — | — | US | claimed |
| US-20080033174-A1 | Method for the Production of 3-Phenyl (Thio) Uracils and Dithiouracils | BASF AKTIENGESELLSCHAFT (DE) | 2008-02-07 | — | — | US | claimed |
| EP-1692115-B1 | METHOD FOR PRODUCING 3-PHENYL(THIO)URACILS AND 3-PHENYLDITHIOURACILS | BASF AG (DE) | 2007-12-19 | — | — | EP | claimed |
| EP-1773787-A1 | METHOD FOR THE PRODUCTION OF 3-PHENYL(THIO)URACILS AND DITHIOURACILS | BASF AKTIENGESELLSCHAFT (DE) | 2007-04-18 | — | — | EP | claimed |
| US-20060293520-A1 | Mehtod for producing 3-phenyl(thio)uracils and 3-phenyldithiouracils | BASF AKTIENGESELLSCHAFT (DE) | 2006-12-28 | — | — | US | claimed |
| EP-1692115-A1 | METHOD FOR PRODUCING 3-PHENYL(THIO)URACILS AND 3-PHENYLDITHIOURACILS | BASF AKTIENGESELLSCHAFT (DE) | 2006-08-23 | — | — | EP | claimed |
| WO-2006010474-A1 | METHOD FOR THE PRODUCTION OF 3-PHENYL(THIO)URACILS AND DITHIOURACILS | BASF AKTIENGESELLSCHAFT (DE) | 2006-02-02 | — | — | WO | claimed |
| WO-2005054208-A1 | METHOD FOR PRODUCING 3-PHENYL(THIO)URACILS AND 3-PHENYLDITHIOURACILS | BASF AKTIENGESELLSCHAFT (DE) | 2005-06-16 | — | — | WO | claimed |
| CN-1989111-B | Method for the production of 3-phenyl(thio)uracils and dithiouracils | BASF AG | 2012-12-05 | — | — | CN | disclosed |
| CN-1989111-B | Method for the production of 3-phenyl(thio)uracils and dithiouracils | BASF AG | 2012-12-05 | — | — | CN | disclosed |
| US-8252925-B2 | Method for the production of 3-phenyl(thio)uracils and dithiouracils | BASF AKTIENGESELLSCHAFT (DE) | 2012-08-28 | — | — | US | disclosed |
| US-8252925-B2 | Method for the production of 3-phenyl(thio)uracils and dithiouracils | BASF AKTIENGESELLSCHAFT (DE) | 2012-08-28 | — | — | US | disclosed |
| US-8252925-B2 | Method for the production of 3-phenyl(thio)uracils and dithiouracils | BASF AKTIENGESELLSCHAFT (DE) | 2012-08-28 | — | — | US | disclosed |
| EP-1692115-A1 | METHOD FOR PRODUCING 3-PHENYL(THIO)URACILS AND 3-PHENYLDITHIOURACILS | BASF AKTIENGESELLSCHAFT (DE) | 2006-08-23 | — | — | EP | disclosed |
| EP-1692115-A1 | METHOD FOR PRODUCING 3-PHENYL(THIO)URACILS AND 3-PHENYLDITHIOURACILS | BASF AKTIENGESELLSCHAFT (DE) | 2006-08-23 | — | — | EP | disclosed |
| WO-2006010474-A1 | METHOD FOR THE PRODUCTION OF 3-PHENYL(THIO)URACILS AND DITHIOURACILS | BASF AKTIENGESELLSCHAFT (DE) | 2006-02-02 | — | — | WO | disclosed |
| WO-2006010474-A1 | METHOD FOR THE PRODUCTION OF 3-PHENYL(THIO)URACILS AND DITHIOURACILS | BASF AKTIENGESELLSCHAFT (DE) | 2006-02-02 | — | — | WO | disclosed |
| WO-2005054208-A1 | METHOD FOR PRODUCING 3-PHENYL(THIO)URACILS AND 3-PHENYLDITHIOURACILS | BASF AKTIENGESELLSCHAFT (DE) | 2005-06-16 | — | — | WO | disclosed |
| WO-2005054208-A1 | METHOD FOR PRODUCING 3-PHENYL(THIO)URACILS AND 3-PHENYLDITHIOURACILS | BASF AKTIENGESELLSCHAFT (DE) | 2005-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060293520-A1 | Mehtod for producing 3-phenyl(thio)uracils and 3-phenyldithiouracils | HPRT1, TH, METTL3 | GSK3A 4469/4885GSK3B 4728/4885GAA 3726/4885 |
| US-20080033174-A1 | Method for the Production of 3-Phenyl (Thio) Uracils and Dithiouracils | TPMT, TYMP, TYMS | GSK3A 4489/4885GSK3B 4488/4885GAA 1862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.