Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | PPID | Q08752 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7315065 | 0.91 | EBP (0.51) | EBPSIGMAR1SMN1; SMN2POLBCYP4F2 | |
| SCHEMBL7120092 | 0.86 | EBP (0.47) | EBPSIGMAR1KCNA3ABCB1L3MBTL1 | |
| SCHEMBL5751980 | 0.83 | EBP (0.51) | EBPSIGMAR1SMN1; SMN2OPRM1L3MBTL1 | |
| SCHEMBL5230297 | 0.83 | ABCB1 (0.40) | EBPSIGMAR1SMN1; SMN2POLBCYP4F2 | |
| SCHEMBL5753399 | 0.82 | EBP (0.50) | EBPSIGMAR1SMN1; SMN2OPRM1L3MBTL1 | |
| SCHEMBL5752605 | 0.81 | SIGMAR1 (0.47) | EBPSIGMAR1CYP4F2CYP4A11OPRM1 | |
| SCHEMBL7826967 | 0.81 | KCNA3 (0.52) | SMN1; SMN2POLBCYP4F2CYP4A11KCNA3 | |
| SCHEMBL11845684 | 0.81 | SMN1; SMN2 (0.50) | EBPSIGMAR1SMN1; SMN2POLBCYP4F2 | |
| SCHEMBL5751743 | 0.80 | KDM4E (0.40) | CYP4F2CYP4A11L3MBTL1ALDH1A1 | |
| SCHEMBL29983875 | 0.80 | POLB (0.51) | SMN1; SMN2POLBCYP4F2CYP4A11KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6667412-B1 | Carboxylic acid, ester or alcohol derivatives; n,n-substi-tuted cyclic amine or phenylacetonitrile intermediates; low cost; stability, workability, final product purity | EISAI CO., LTD. (JP) | 2003-12-23 | — | — | US | claimed |
| EP-1167348-A1 | NITRILE DERIVATIVES | Eisai Co., Ltd. (JP) | 2002-01-02 | — | — | EP | claimed |
| US-6667412-B1 | Carboxylic acid, ester or alcohol derivatives; n,n-substi-tuted cyclic amine or phenylacetonitrile intermediates; low cost; stability, workability, final product purity | EISAI CO., LTD. (JP) | 2003-12-23 | — | — | US | disclosed |
| EP-1167348-A1 | NITRILE DERIVATIVES | Eisai Co., Ltd. (JP) | 2002-01-02 | — | — | EP | disclosed |