Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 2/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 4/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5751980 | 0.89 | EBP (0.51) | EBPSIGMAR1CYP2D6CYP1A2ALDH1A1 | |
| SCHEMBL5752605 | 0.84 | SIGMAR1 (0.47) | EBPSIGMAR1CYP2D6CYP1A2ALDH1A1 | |
| SCHEMBL7120092 | 0.84 | EBP (0.47) | EBPSIGMAR1CYP2D6CYP1A2ALDH1A1 | |
| SCHEMBL7304642 | 0.82 | EBP (0.54) | EBPSIGMAR1CYP2D6CYP1A2L3MBTL1 | |
| SCHEMBL7306091 | 0.82 | EBP (0.54) | EBPSIGMAR1CYP2D6CYP1A2L3MBTL1 | |
| SCHEMBL7121992 | 0.82 | EBP (0.48) | EBPSIGMAR1CYP2D6ALDH1A1L3MBTL1 | |
| SCHEMBL7753625 | 0.79 | EBP (0.56) | EBPSIGMAR1CYP2D6L3MBTL1CYP3A4 | |
| SCHEMBL5226760 | 0.79 | EBP (0.56) | EBPSIGMAR1CYP2D6CYP1A2L3MBTL1 | |
| SCHEMBL5237762 | 0.78 | EBP (0.59) | EBPSIGMAR1CYP2D6CYP1A2L3MBTL1 | |
| SCHEMBL7310593 | 0.77 | EBP (0.51) | EBPSIGMAR1CYP2D6CYP1A2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1099692-B1 | N,N-SUBSTITUTED CYCLIC AMINE DERIVATIVES | EISAI CO LTD (JP) | 2006-05-03 | — | — | EP | disclosed |
| US-6737425-B1 | SUCH AS 1-((4-CYANO-5-METHYL-4-PHENYL)HEXYL)-4-(2-(4-FLUORO -PHENOXY)ETHYL)PIPERAZINE; NERVE SELECTIVE CALCIUM ANTAGONISTS | EISAI CO., LTD. (JP) | 2004-05-18 | — | — | US | disclosed |
| CN-1310709-A | N, N-substituted cyclic amine derivatives | EISAI CO LTD (JP) | 2001-08-29 | — | — | CN | disclosed |
| EP-1099692-A1 | N,N-SUBSTITUTED CYCLIC AMINE DERIVATIVES | Eisai Co., Ltd. (JP) | 2001-05-16 | — | — | EP | disclosed |