Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7253205 | 0.91 | IGF1R (0.80) | IGF1RALDH1A1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL4498917 | 0.87 | IGF1R (0.54) | IGF1RALDH1A1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL13982876 | 0.85 | ALDH1A1 (0.82) | IGF1RALDH1A1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL94996 | 0.83 | IGF1R (1.00) | IGF1RALDH1A1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL4499070 | 0.83 | RAB9A (0.54) | IGF1RALDH1A1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL172745 | 0.82 | IGF1R (0.64) | IGF1RALDH1A1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL13919312 | 0.81 | IGF1R (0.48) | IGF1RALDH1A1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL94970 | 0.81 | IGF1R (0.70) | IGF1RALDH1A1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL25295408 | 0.78 | SMN1; SMN2 (0.58) | IGF1RALDH1A1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL4193955 | 0.78 | ALDH1A1 (0.62) | IGF1RALDH1A1KMT2APOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003035616-A2 | TYROSINE KINASE INHIBITORS | MERCK & CO., INC. (US) | 2003-05-01 | — | — | WO | disclosed |