Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | IGF1R | P08069 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7120457 | 0.94 | RAB9A (0.53) | RAB9ANPC1KMT2AIGF1RMAPK1 | |
| SCHEMBL7121375 | 0.89 | IGF1R (0.57) | RAB9ANPC1KMT2AIGF1RMAPK1 | |
| SCHEMBL7119893 | 0.89 | IGF1R (0.70) | RAB9ANPC1KMT2AIGF1RHPGD | |
| SCHEMBL7119100 | 0.87 | RAB9A (0.59) | RAB9ANPC1KMT2AIGF1RMAPK1 | |
| SCHEMBL4203572 | 0.84 | RAB9A (0.65) | RAB9ANPC1KMT2AIGF1RMAPK1 | |
| SCHEMBL7119088 | 0.84 | IGF1R (0.69) | RAB9ANPC1KMT2AIGF1RHPGD | |
| SCHEMBL7122759 | 0.81 | IGF1R (0.76) | IGF1RMAPK1HPGDALDH1A1HTT | |
| SCHEMBL13574871 | 0.80 | IGF1R (0.62) | IGF1RMAPK1HPGDALDH1A1HTT | |
| SCHEMBL7114812 | 0.80 | IGF1R (0.73) | RAB9ANPC1KMT2AIGF1RHPGD | |
| SCHEMBL94596 | 0.77 | IGF1R (0.59) | RAB9ANPC1KMT2AIGF1RMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003035616-A2 | TYROSINE KINASE INHIBITORS | MERCK & CO., INC. (US) | 2003-05-01 | — | — | WO | disclosed |