Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20480680 | 0.91 | CYSLTR2 (0.43) | KDM4EALDH1A1SMN1; SMN2PLA2G2DCYSLTR2 | |
| SCHEMBL126602 | 0.88 | PLA2G2D (0.42) | KDM4EALDH1A1SMN1; SMN2PLA2G2DCYSLTR2 | |
| SCHEMBL303215 | 0.88 | PLA2G2D (0.42) | KDM4EALDH1A1SMN1; SMN2PLA2G2DCYSLTR2 | |
| SCHEMBL8523379 | 0.82 | THRB (0.43) | KDM4EALDH1A1SMN1; SMN2PLA2G2DCYSLTR2 | |
| SCHEMBL8523376 | 0.82 | THRB (0.43) | KDM4EALDH1A1SMN1; SMN2PLA2G2DCYSLTR2 | |
| SCHEMBL19183552 | 0.82 | THRB (0.40) | KDM4EALDH1A1SMN1; SMN2PLA2G2DCYSLTR2 | |
| SCHEMBL9556877 | 0.82 | THRB (0.40) | KDM4EALDH1A1SMN1; SMN2PLA2G2DCYSLTR2 | |
| Coumarinic Acid Methyl Ether SCHEMBL14889493 | 0.81 | GAA (0.50) | KDM4EALDH1A1SMN1; SMN2PLA2G2DKMT2A | |
| SCHEMBL7119159 | 0.80 | THRB (0.39) | KDM4EALDH1A1SMN1; SMN2PLA2G2DCYSLTR2 | |
| SCHEMBL8025820 | 0.78 | PLA2G2D (0.42) | KDM4EALDH1A1SMN1; SMN2PLA2G2DCYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0756477-B1 | METHODS FOR PHOTOTHERAPEUTIC TREATMENT OF PROLIFERATIVE SKIN DISEASES | GEN HOSPITAL CORP (US) | 2003-11-19 | — | — | EP | disclosed |