Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.40 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8523379 | 1.00 | THRB (0.43) | THRBATMMAPTALDH1A1MEN1 | |
| SCHEMBL20480680 | 0.88 | CYSLTR2 (0.43) | THRBATMMAPTALDH1A1MEN1 | |
| SCHEMBL303215 | 0.87 | PLA2G2D (0.42) | THRBATMMAPTALDH1A1MEN1 | |
| SCHEMBL126602 | 0.87 | PLA2G2D (0.42) | THRBATMMAPTALDH1A1MEN1 | |
| SCHEMBL7119159 | 0.85 | THRB (0.39) | THRBATMMAPTALDH1A1MEN1 | |
| SCHEMBL9556877 | 0.85 | THRB (0.40) | THRBATMMAPTALDH1A1MEN1 | |
| SCHEMBL19183552 | 0.85 | THRB (0.40) | THRBATMMAPTALDH1A1MEN1 | |
| SCHEMBL7122374 | 0.82 | KDM4E (0.40) | THRBATMMAPTALDH1A1MEN1 | |
| SCHEMBL490210 | 0.81 | THRB (0.53) | THRBATMMAPTALDH1A1MEN1 | |
| SCHEMBL490211 | 0.81 | THRB (0.53) | THRBATMMAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5989529-A | Substantive topical composition | SCHERING-PLOUGH HEALTHCARE PRODUCTS, INC. (US) | 1999-11-23 | — | — | US | disclosed |
| US-5247121-A | Cosmetics | L'OREAL (FR) | 1993-09-21 | — | — | US | disclosed |
| US-5112601-A | Cosmetics | L'OREAL (FR) | 1992-05-12 | — | — | US | disclosed |