Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 15/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7128378 | 0.91 | GAA (0.43) | F10PRSS1F2GAAITGB3 | |
| SCHEMBL7124835 | 0.83 | F10 (0.55) | F10PRSS1F2 | |
| SCHEMBL7122641 | 0.79 | GAA (0.43) | GAA | |
| SCHEMBL7127217 | 0.67 | F10 (0.65) | F10PRSS1F2 | |
| SCHEMBL7123485 | 0.66 | F10 (1.00) | F10PRSS1F2 | |
| SCHEMBL7484805 | 0.65 | F10 (1.00) | F10PRSS1F2 | |
| SCHEMBL7126469 | 0.65 | KDM4E (0.56) | — | |
| SCHEMBL7481885 | 0.65 | F10 (1.00) | F10PRSS1F2 | |
| Hydrochloric Acid SCHEMBL5091274 | 0.63 | P2RX4 (0.53) | F10PRSS1F2 | |
| SCHEMBL7116303 | 0.63 | PRSS1 (0.59) | F10PRSS1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030114448-A1 | Inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. | 2003-06-19 | — | — | US | disclosed |
| WO-2002096873-A1 | ISOINDOLE AND ISOQUINOLINE DERIVATIVES AS INHIBITORS OF FACTOR XA | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-12-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030114448-A1 | Inhibitors of factor Xa | SERPINC1, F11, TFPI | F10 7/4885PRSS1 59/4885F2 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.