Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.42 |
| ▸ | PTPN7 | P35236 | 4/20 | 0.41 |
| ▸ | HMGCR | P04035 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5985617 | 0.86 | HMGCR (0.36) | DNM1PTPN7HMGCR | |
| SCHEMBL19432981 | 0.84 | DNM1 (0.39) | DNM1HMGCRTDP1TSHR | |
| SCHEMBL157112 | 0.84 | LMNA (0.47) | PTPN7HMGCRRECQLTDP1 | |
| SCHEMBL25939926 | 0.83 | EPHX1 (0.47) | PTPN7HMGCRRECQLTDP1 | |
| SCHEMBL28567418 | 0.83 | HMGCR (0.37) | PTPN7HMGCRRECQLTDP1 | |
| SCHEMBL31230828 | 0.83 | TSHR (0.36) | DNM1PTPN7HMGCRTSHR | |
| SCHEMBL8649300 | 0.81 | HMGCR (0.38) | PTPN7HMGCRRECQLTDP1 | |
| SCHEMBL9626182 | 0.80 | PTPN7 (0.69) | PTPN7HMGCRRECQLTDP1TSHR | |
| SCHEMBL19434123 | 0.79 | CYP3A4 (0.37) | DNM1TDP1TSHR | |
| SCHEMBL60064 | 0.79 | HMGCR (0.40) | PTPN7HMGCRRECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918802-B2 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | BASELL TECHNOLOGY CO BV (NL) | 2004-10-06 | — | — | EP | claimed |
| EP-0918802-B1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | BASELL TECHNOLOGY CO BV (NL) | 2001-11-14 | — | — | EP | claimed |