Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | IP6K1 | Q92551 | 6/20 | 0.33 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.32 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7119514 | 0.82 | POLB (0.55) | ALDH1A1HTTKDM4ELMNAHPGD | |
| SCHEMBL7119641 | 0.66 | HTT (0.71) | ALDH1A1HTTKDM4EHPGDCYP1A2 | |
| SCHEMBL7115705 | 0.66 | HTT (0.71) | ALDH1A1HTTKDM4EHPGDCYP1A2 | |
| SCHEMBL7119569 | 0.64 | HTT (0.44) | ALDH1A1HTTKDM4ECYP1A2CYP2C9 | |
| SCHEMBL7128300 | 0.64 | HTT (0.73) | ALDH1A1HTTKDM4EHPGDCYP1A2 | |
| SCHEMBL19705078 | 0.63 | POLB (0.46) | ALDH1A1HTTPOLBIP6K1IP6K3 | |
| SCHEMBL7122779 | 0.62 | ALDH1A1 (0.41) | ALDH1A1HTTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL569208 | 0.59 | HPGD (0.42) | ALDH1A1HTTKDM4ELMNAHPGD | |
| SCHEMBL856968 | 0.58 | KDM4E (0.41) | ALDH1A1HTTKDM4ELMNAHPGD | |
| SCHEMBL30785316 | 0.58 | GRM5 (0.36) | ALDH1A1HTTKDM4ELMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030096813-A1 | Compositions useful as inhibitors of GSK-3 | CAO JINGRONG (US) | 2003-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030096813-A1 | Compositions useful as inhibitors of GSK-3 | GSK3B, GSK3A, GSKIP | ALDH1A1 3164/4885HTT 2576/4885KDM4E 1667/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.