Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7115705 | 0.72 | HTT (0.71) | ALDH1A1CYP1A2CYP2C9CYP2C19RAB9A | |
| SCHEMBL7119641 | 0.72 | HTT (0.71) | ALDH1A1CYP1A2CYP2C9CYP2C19RAB9A | |
| SCHEMBL7128300 | 0.71 | HTT (0.73) | ALDH1A1CYP1A2CYP2C9CYP2C19RAB9A | |
| SCHEMBL7119569 | 0.71 | HTT (0.44) | ALDH1A1CYP1A2CYP2C9CYP2C19RAB9A | |
| SCHEMBL7122760 | 0.62 | ALDH1A1 (0.42) | ALDH1A1CYP1A2CYP2C9CYP2C19RAB9A | |
| SCHEMBL6920444 | 0.58 | HTT (0.97) | ALDH1A1CYP1A2CYP2C9CYP2C19RAB9A | |
| SCHEMBL7118898 | 0.58 | HTT (0.97) | ALDH1A1CYP1A2CYP2C9CYP2C19RAB9A | |
| SCHEMBL6918782 | 0.58 | HTT (0.53) | ALDH1A1CYP1A2CYP2C9CYP2C19RAB9A | |
| SCHEMBL6919069 | 0.56 | HTT (1.00) | ALDH1A1CYP1A2CYP2C9CYP2C19RAB9A | |
| SCHEMBL32665703 | 0.52 | ADH5 (0.43) | ALDH1A1POLBRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030096813-A1 | Compositions useful as inhibitors of GSK-3 | CAO JINGRONG (US) | 2003-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030096813-A1 | Compositions useful as inhibitors of GSK-3 | GSK3B, GSK3A, GSKIP | ALDH1A1 3164/4885CYP1A2 1893/4885CYP2C9 2417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.