Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.38 |
| ▸ | NQO1 | P15559 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4172887 | 0.83 | LMNA (0.54) | LMNAHTTPKMPTGS1PTGS2 | |
| SCHEMBL3319014 | 0.82 | CYP1A2 (0.46) | MEN1NPC1HSP90AA1RAB9AKMT2A | |
| SCHEMBL482566 | 0.81 | LMNA (0.38) | LMNAHTTPKMMEN1NPC1 | |
| SCHEMBL31320884 | 0.80 | CYP1A2 (0.44) | MEN1NPC1HSP90AA1RAB9AKMT2A | |
| SCHEMBL31320889 | 0.80 | CYP1A2 (0.44) | MEN1NPC1HSP90AA1RAB9AKMT2A | |
| SCHEMBL28225839 | 0.80 | CYP1A2 (0.44) | MEN1NPC1HSP90AA1RAB9AKMT2A | |
| SCHEMBL31320910 | 0.80 | CYP1A2 (0.44) | MEN1NPC1HSP90AA1RAB9AKMT2A | |
| SCHEMBL31320819 | 0.80 | CYP1A2 (0.44) | MEN1NPC1HSP90AA1RAB9AKMT2A | |
| SCHEMBL31320923 | 0.80 | CYP1A2 (0.44) | MEN1NPC1HSP90AA1RAB9AKMT2A | |
| SCHEMBL30845731 | 0.79 | CYP1A2 (0.46) | LMNAHTTPKMMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003031937-A2 | GENETIC HYPERMUTABILITY OF PLANTS FOR GENE DISCOVERY AND DIAGNOSIS | MORPHOTEK, INC. (US) | 2003-04-17 | — | — | WO | claimed |