Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | GFER | P55789 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL33801 | 0.94 | TDP1 (0.67) | CYP3A4TDP1ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL10300283 | 0.89 | HRH3 (0.48) | CYP3A4TDP1ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL7155728 | 0.89 | HRH3 (0.48) | CYP3A4TDP1ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL27461663 | 0.88 | CYP3A4 (0.55) | CYP3A4TDP1ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL6822008 | 0.88 | ALDH1A1 (0.79) | CYP3A4TDP1ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL2790604 | 0.86 | ALDH1A1 (0.53) | CYP3A4TDP1ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL13949611 | 0.86 | CYP3A4 (0.57) | CYP3A4TDP1ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL7520164 | 0.85 | ALDH1A1 (0.75) | CYP3A4TDP1ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL7121739 | 0.85 | ALDH1A1 (0.52) | CYP3A4TDP1ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL19415813 | 0.84 | TDP1 (0.55) | CYP3A4TDP1ALDH1A1L3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030134859-A1 | PPAR-gamma modulator | SANKYO COMPANY, LIMITED (JP) | 2003-07-17 | — | — | US | disclosed |
| EP-1277729-A1 | PPAR (GAMMA) MODULATORS | Sankyo Company, Limited (JP) | 2003-01-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030134859-A1 | PPAR-gamma modulator | PPARG, PPARA, PPARD | CYP3A4 1516/4885TDP1 4823/4885ALDH1A1 583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.