SCHEMBL7520164

SCHEMBL7520164

CCCN(CC)c1ccc(N)cc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.75
CYP3A4 P08684 3/20 0.75
TDP1 Q9NUW8 3/20 0.75
MAPK1 P28482 2/20 0.75
L3MBTL1 Q9Y468 2/20 0.75
TSHR P16473 2/20 0.75
PSMD14 O00487 1/20 0.75
RECQL P46063 1/20 0.75
GFER P55789 1/20 0.75
TP53 P04637 1/20 0.44
ALOX15 P16050 1/20 0.44
S100B P04271 1/20 0.42
ALDH3A1 P30838 1/20 0.42
ALDH1A3 P47895 1/20 0.42
MAPT P10636 2/20 0.41
KDM4E B2RXH2 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6822008 0.94 ALDH1A1 (0.79) ALDH1A1CYP3A4TDP1MAPK1L3MBTL1
SCHEMBL33801 0.91 TDP1 (0.67) ALDH1A1CYP3A4TDP1MAPK1L3MBTL1
SCHEMBL29740663 0.91 ALDH1A1 (0.82) ALDH1A1CYP3A4TDP1MAPK1L3MBTL1
SCHEMBL33781 0.86 ALDH1A1 (1.00) ALDH1A1CYP3A4TDP1MAPK1L3MBTL1
SCHEMBL8467252 0.86 ALDH1A1 (1.00) ALDH1A1CYP3A4TDP1MAPK1L3MBTL1
SCHEMBL25189789 0.86 TDP1 (0.67) ALDH1A1CYP3A4TDP1MAPK1L3MBTL1
SCHEMBL7122869 0.85 CYP3A4 (0.59) ALDH1A1CYP3A4TDP1MAPK1L3MBTL1
SCHEMBL6389743 0.85 ALDH1A1 (0.72) ALDH1A1CYP3A4TDP1MAPK1L3MBTL1
SCHEMBL30678627 0.84 TDP1 (0.64) ALDH1A1CYP3A4TDP1MAPK1L3MBTL1
Hydrochloric Acid SCHEMBL970321 0.84 ALDH1A1 (0.95) ALDH1A1CYP3A4TDP1MAPK1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020170122-A9 Compositions for the oxidation dyeing of keratinous fibers comprising at least one oxidation dye and at least one enzymatic oxidizing agent, and dyeing methods L'OREAL S.A. (FR) 2002-11-21 US claimed
EP-0250219-B1 Method of storing photographic processing solution KONISHIROKU PHOTO IND (JP) 1994-03-30 EP disclosed
US-4814260-A USING DEVELOPER WITH SUBSTITUTED HYDROXYLAMINE PRESERVATIVE; BLEACH-FIXER WITH REDUCED AMOUNTS OF AMINOPOLYCARBOXYLIC ACID AND SULFITE KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1989-03-21 US disclosed
EP-0250219-A2 Method of storing photographic processing solution KONICA CORPORATION (JP) 1987-12-23 EP disclosed
US-4520093-A COMPENSATING PIGMENTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-05-28 US disclosed
US-4504568-A Sensitive silver halide photothermographic materials for producing dye images EASTMAN KODAK COMPANY (US) 1985-03-12 US disclosed
EP-0052942-B1 PHOTOIMAGING PROCESS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-03-28 EP disclosed
US-4335197-A SILVER HALIDE DISPERSION IN FILM-FORMING POLYMERIC COUPLER E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-06-15 US disclosed
EP-0052942-A1 Photoimaging process E.I. DU PONT DE NEMOURS AND COMPANY (US) 1982-06-02 EP disclosed
US-4233399-A Photographic elements containing amino-substituted hydroxy-pyridones CIBA-GEIGY AKTIENGESELLSCHAFT (CH) 1980-11-11 US disclosed
US-4182886-A OPTICAL FILTERS IN COLOR PHOTOGRAPHY CIBA-GEIGY AKTIENGESELLSCHAFT (CH) 1980-01-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020170122-A9 Compositions for the oxidation dyeing of keratinous fibers comprising at least one oxidation dye and at least one enzymatic oxidizing agent, and dyeing methods KRT18, PPOX, AOX1 ALDH1A1 104/4885CYP3A4 390/4885TDP1 1275/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.