Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7164705 | 1.00 | SGMS2 (0.57) | SGMS2NPC1LMNAMAPTL3MBTL1 | |
| SCHEMBL1097807 | 1.00 | SGMS2 (0.57) | SGMS2NPC1LMNAMAPTL3MBTL1 | |
| SCHEMBL9642440 | 0.89 | SGMS2 (0.59) | SGMS2NPC1LMNAMAPTL3MBTL1 | |
| SCHEMBL1097809 | 0.89 | SGMS2 (0.59) | SGMS2NPC1LMNAMAPTL3MBTL1 | |
| SCHEMBL10442994 | 0.89 | SGMS2 (0.52) | SGMS2NPC1LMNAMAPTL3MBTL1 | |
| SCHEMBL5046789 | 0.89 | SGMS2 (0.52) | SGMS2NPC1LMNAMAPTL3MBTL1 | |
| SCHEMBL5046787 | 0.89 | SGMS2 (0.52) | SGMS2NPC1LMNAMAPTL3MBTL1 | |
| SCHEMBL9647587 | 0.88 | SGMS2 (0.47) | SGMS2NPC1LMNAMAPTL3MBTL1 | |
| SCHEMBL9730334 | 0.88 | SGMS2 (0.47) | SGMS2NPC1LMNAMAPTL3MBTL1 | |
| SCHEMBL10443318 | 0.88 | SGMS2 (0.58) | SGMS2NPC1LMNAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2308825-B1 | Process for the preparation of an intermediate for azoxystrobin | SYNGENTA LTD (GB) | 2014-05-21 | — | — | EP | disclosed |
| EP-1891020-B1 | PROCESSES FOR THE PREPARATION OF AZOXYSTROBIN USING DABCO AS A CATALYST AND NOVEL INTERMEDIATES USED IN THE PROCESSES | SYNGENTA LTD (GB) | 2013-06-05 | — | — | EP | disclosed |
| US-8124761-B2 | Coupling of methyl (E)-2-{2-[6-chloropyrimidin-4-yloxy]phenyl}-3-methoxyacrylate with 2-cyanophenyl in DMF with 2 mol % DABCO; significantly smaller amounts of this relatively expensive catalyst may be used without compromising the yield | SYNGENTA LIMITED (GB) | 2012-02-28 | — | — | US | disclosed |
| US-8124761-B2 | Coupling of methyl (E)-2-{2-[6-chloropyrimidin-4-yloxy]phenyl}-3-methoxyacrylate with 2-cyanophenyl in DMF with 2 mol % DABCO; significantly smaller amounts of this relatively expensive catalyst may be used without compromising the yield | SYNGENTA LIMITED (GB) | 2012-02-28 | — | — | US | disclosed |
| US-8124761-B2 | Coupling of methyl (E)-2-{2-[6-chloropyrimidin-4-yloxy]phenyl}-3-methoxyacrylate with 2-cyanophenyl in DMF with 2 mol % DABCO; significantly smaller amounts of this relatively expensive catalyst may be used without compromising the yield | SYNGENTA LIMITED (GB) | 2012-02-28 | — | — | US | disclosed |
| EP-2308825-A1 | Process for the preparation of an intermediate for azoxystrobin | Syngenta Limited (GB) | 2011-04-13 | — | — | EP | disclosed |
| EP-2308825-A1 | Process for the preparation of an intermediate for azoxystrobin | Syngenta Limited (GB) | 2011-04-13 | — | — | EP | disclosed |
| US-20080214587-A1 | Processes For the Preparation of Azoxystrobin Using Dabco as a Catalyst and Novel Intermediates Used in the Processes | SYNGENTA CROP PROTECTION, INC. (US) | 2008-09-04 | — | — | US | disclosed |
| US-20080214587-A1 | Processes For the Preparation of Azoxystrobin Using Dabco as a Catalyst and Novel Intermediates Used in the Processes | SYNGENTA CROP PROTECTION, INC. (US) | 2008-09-04 | — | — | US | disclosed |
| EP-0178826-B2 | Fungicides | SYNGENTA LTD (GB) | 2003-04-09 | — | — | EP | disclosed |
| US-5602076-A | INSECTICIDES, NEMATOCIDES | ZENECA LIMITED (GB) | 1997-02-11 | — | — | US | disclosed |
| US-5470819-A | Plant growth regulators, insecticides | ZENECA LIMITED (GB) | 1995-11-28 | — | — | US | disclosed |
| EP-0260794-B1 | Substituted phenyl-2-propenoic acid derivatives and their use as fungicides | ZENECA LTD (GB) | 1994-06-22 | — | — | EP | disclosed |
| EP-0256667-B1 | SUBSTITUTED PHENYL-2-PROPENOIC ACID DERIVATIVES USEFUL IN AGRICULTURE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-12-30 | — | — | EP | disclosed |
| US-5120755-A | FUNGICIDAL SUBSTITUTED ACRYLIC ACID ESTERS | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-09 | — | — | US | disclosed |
| EP-0178826-B1 | FUNGICIDES | ZENECA LIMITED (GB) | 1991-12-18 | — | — | EP | disclosed |
| US-5057146-A | CERTAIN 2-PYRIDYL OXY-PHENYL ACRYLATES HAVING FUNGICIDAL, INSECTICIDAL, NEMATOCIDAL AND PLANT GROWTH REGULATING ACTIVITY | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-10-15 | — | — | US | disclosed |
| EP-0391451-A1 | Fungicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-10-10 | — | — | EP | disclosed |
| EP-0387923-A2 | Fungicides | ZENECA LIMITED (GB) | 1990-09-19 | — | — | EP | disclosed |
| EP-0242081-A1 | Fungicides | ZENECA LIMITED (GB) | 1987-10-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080214587-A1 | Processes For the Preparation of Azoxystrobin Using Dabco as a Catalyst and Novel Intermediates Used in the Processes | DDT, AOC3, DAO | SGMS2 4000/4885NPC1 4635/4885LMNA 3353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.