Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7164705 | 1.00 | SGMS2 (0.57) | SGMS2NPC1LMNAMAPTL3MBTL1 | |
| SCHEMBL712291 | 1.00 | SGMS2 (0.57) | SGMS2NPC1LMNAMAPTL3MBTL1 | |
| SCHEMBL9642440 | 0.89 | SGMS2 (0.59) | SGMS2NPC1LMNAMAPTL3MBTL1 | |
| SCHEMBL1097809 | 0.89 | SGMS2 (0.59) | SGMS2NPC1LMNAMAPTL3MBTL1 | |
| SCHEMBL10442994 | 0.89 | SGMS2 (0.52) | SGMS2NPC1LMNAMAPTL3MBTL1 | |
| SCHEMBL5046789 | 0.89 | SGMS2 (0.52) | SGMS2NPC1LMNAMAPTL3MBTL1 | |
| SCHEMBL5046787 | 0.89 | SGMS2 (0.52) | SGMS2NPC1LMNAMAPTL3MBTL1 | |
| SCHEMBL9647587 | 0.88 | SGMS2 (0.47) | SGMS2NPC1LMNAMAPTL3MBTL1 | |
| SCHEMBL9730334 | 0.88 | SGMS2 (0.47) | SGMS2NPC1LMNAMAPTL3MBTL1 | |
| SCHEMBL10443318 | 0.88 | SGMS2 (0.58) | SGMS2NPC1LMNAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6566547-B1 | 3-alkoxy-2-phenylacrylic acid derivatives | ZENECA LIMITED (GB) | 2003-05-20 | — | — | US | claimed |
| EP-0203608-B2 | ACRYLIC-ACID ESTERS AND FUNGICIDES CONTAINING THESE COMPOUNDS | BASF Aktiengesellschaft (DE) | 1989-09-06 | — | — | EP | claimed |
| EP-0203608-B1 | ACRYLIC-ACID ESTERS AND FUNGICIDES CONTAINING THESE COMPOUNDS | BASF Aktiengesellschaft (DE) | 1988-01-07 | — | — | EP | claimed |
| US-4709078-A | Acrylates, and fungicides which contain these compounds | BASF AKTIENGESELLSCHAFT (DE) | 1987-11-24 | — | — | US | claimed |
| EP-0203608-A1 | Acrylic-acid esters and fungicides containing these compounds | BASF Aktiengesellschaft (DE) | 1986-12-03 | — | — | EP | claimed |
| EP-2148854-B1 | ESTERS OF 2-PHENYLALKANENITRILES AND ANTIFUNGAL COMPOSITIONS CONTAINING THEM | STOUTAMIRE DONALD WESLEY (US) | 2013-02-20 | — | — | EP | disclosed |
| US-8153688-B2 | Esters of 2-phenylalkanenitriles and antifungal compositions containing them | MCS Laboratories, Inc. (US) | 2012-04-10 | — | — | US | disclosed |
| US-20100022640-A1 | ESTERS OF 2-PHENYLALKANENITRILES AND ANTIFUNGAL COMPOSITIONS CONTAINING THEM | MCS LABORATORIES INC. | 2010-01-28 | — | — | US | disclosed |
| US-7622504-B2 | Esters of 2-phenylalkanenitriles and antifungal compositions containing them | MCS Laboratories, Inc. (US) | 2009-11-24 | — | — | US | disclosed |
| US-20080153905-A1 | Esters of 2-phenylalkanenitriles and antifungal compositions containing them | MCS LABORATORIES INC. | 2008-06-26 | — | — | US | disclosed |
| EP-0178826-B2 | Fungicides | SYNGENTA LTD (GB) | 2003-04-09 | — | — | EP | disclosed |
| EP-0350691-B2 | Heterocyclically substituted alpha-aryl-acrylic-acid esters, and fungicides containing these compounds | BASF AG (DE) | 1999-07-28 | — | — | EP | disclosed |
| US-5008438-A | Ortho-substituted phenol ethers and fungicides which contain these compounds | BASF AKTIENGESELLSCHAFT (DE) | 1991-04-16 | — | — | US | disclosed |
| EP-0251082-B1 | SUBSTITUTED ACRYLIC ACID ESTERS AND FUNGICIDES CONTAINING THESE COMPOUNDS | BASF Aktiengesellschaft (DE) | 1990-05-23 | — | — | EP | disclosed |
| EP-0350691-A2 | Heterocyclically substituted alpha-aryl-acrylic-acid esters, and fungicides containing these compounds | BASF Aktiengesellschaft (DE) | 1990-01-17 | — | — | EP | disclosed |
| EP-0336211-A1 | Ortho-substituted phenol ethers and fungicides containing them | BASF Aktiengesellschaft (DE) | 1989-10-11 | — | — | EP | disclosed |
| EP-0331966-A1 | Substituted acrylic-acid esters | BAYER AG (DE) | 1989-09-13 | — | — | EP | disclosed |
| US-4822908-A | Substituted acrylates and fungicides containing same | BASF AKTIENGESELLSCHAFT (DE) | 1989-04-18 | — | — | US | disclosed |
| EP-0251082-A2 | Substituted acrylic acid esters and fungicides containing these compounds | BASF Aktiengesellschaft (DE) | 1988-01-07 | — | — | EP | disclosed |
| US-4709078-A | Acrylates, and fungicides which contain these compounds | BASF AKTIENGESELLSCHAFT (DE) | 1987-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100022640-A1 | ESTERS OF 2-PHENYLALKANENITRILES AND ANTIFUNGAL COMPOSITIONS CONTAINING THEM | CYP51A1, ERG28, AKR7A2 | SGMS2 117/4885NPC1 182/4885LMNA 3014/4885 |
| US-20080153905-A1 | Esters of 2-phenylalkanenitriles and antifungal compositions containing them | CYP51A1, ERG28, AKR7A2 | SGMS2 117/4885NPC1 182/4885LMNA 3014/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.