SCHEMBL7122971

SCHEMBL7122971

CCc1ccc(S(=O)(=O)Nc2ccc(N)cc2)cc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
UCHL1 P09936 1/20 0.76
KMT2A Q03164 3/20 0.67
L3MBTL1 Q9Y468 1/20 0.67
HTT P42858 2/20 0.65
CA1 P00915 1/20 0.65
CA2 P00918 1/20 0.65
CA9 Q16790 1/20 0.65
ALDH1A1 P00352 3/20 0.62
MAPT P10636 3/20 0.62
MEN1 O00255 1/20 0.62
CYP1A2 P05177 1/20 0.62
CYP3A4 P08684 1/20 0.62
CYP2C19 P33261 1/20 0.62
KEAP1 Q14145 1/20 0.62
GHSR Q92847 1/20 0.61
FFAR4 Q5NUL3 1/20 0.60
PRMT1 Q99873 1/20 0.58
HTR6 P50406 1/20 0.57
NPSR1 Q6W5P4 1/20 0.56
TP53 P04637 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11793140 0.86 CA1 (0.85) KMT2AHTTCA1CA2CA9
SCHEMBL540915 0.86 CA1 (0.85) KMT2AHTTCA1CA2CA9
SCHEMBL13596677 0.85 UCHL1 (0.78) UCHL1KMT2AL3MBTL1HTTCA1
SCHEMBL19398863 0.84 KMT2A (0.68) UCHL1KMT2AHTTCA1CA2
SCHEMBL6302353 0.83 UCHL1 (0.76) UCHL1KMT2AL3MBTL1HTTALDH1A1
SCHEMBL2972536 0.83 UCHL1 (0.76) UCHL1KMT2AL3MBTL1HTTALDH1A1
SCHEMBL19234560 0.83 UCHL1 (0.76) UCHL1KMT2AL3MBTL1HTTALDH1A1
SCHEMBL6553107 0.83 UCHL1 (0.76) UCHL1KMT2AL3MBTL1HTTALDH1A1
SCHEMBL19234503 0.83 UCHL1 (0.76) UCHL1KMT2AL3MBTL1HTTCA1
SCHEMBL28412418 0.83 UCHL1 (0.76) UCHL1KMT2AL3MBTL1HTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117186049-A 2, 2-dimethyl-2H chromene derivative containing sulfonamide unit, and preparation method and application thereof 贵州大学 2023-12-08 CN disclosed
US-20030134859-A1 PPAR-gamma modulator SANKYO COMPANY, LIMITED (JP) 2003-07-17 US disclosed
EP-1277729-A1 PPAR (GAMMA) MODULATORS Sankyo Company, Limited (JP) 2003-01-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030134859-A1 PPAR-gamma modulator PPARG, PPARA, PPARD UCHL1 4412/4885KMT2A 3291/4885L3MBTL1 2640/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.