Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 1/20 | 0.76 |
| ▸ | CES1 | P23141 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | XBP1 | P17861 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19234560 | 1.00 | UCHL1 (0.76) | UCHL1CES1KMT2AL3MBTL1HTT | |
| Acetic Acid SCHEMBL8970517 | 0.93 | UCHL1 (0.66) | UCHL1CES1KMT2AL3MBTL1HTT | |
| SCHEMBL24324833 | 0.87 | CES1 (0.69) | UCHL1CES1HTTALDH1A1TDP1 | |
| SCHEMBL2474197 | 0.86 | CES1 (1.00) | CES1KMT2AHTTALDH1A1TDP1 | |
| SCHEMBL6554630 | 0.86 | CES1 (1.00) | CES1KMT2AHTTALDH1A1TDP1 | |
| SCHEMBL13596677 | 0.85 | UCHL1 (0.78) | UCHL1KMT2AL3MBTL1HTTALDH1A1 | |
| SCHEMBL27812546 | 0.84 | FFAR1 (0.74) | CES1HTTALDH1A1TDP1LMNA | |
| SCHEMBL7122971 | 0.83 | UCHL1 (0.76) | UCHL1KMT2AL3MBTL1HTTALDH1A1 | |
| SCHEMBL6302353 | 0.83 | UCHL1 (0.76) | UCHL1KMT2AL3MBTL1HTTALDH1A1 | |
| SCHEMBL19234503 | 0.83 | UCHL1 (0.76) | UCHL1KMT2AL3MBTL1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1174028-B1 | SULFONAMIDE DERIVATIVES | SUMITOMO CHEM TAKEDA AGRO CO (JP) | 2004-12-22 | — | — | EP | disclosed |
| US-20040023938-A1 | Sulfonamide derivatives | TABUCHI TAKANORI (JP) | 2004-02-05 | — | — | US | disclosed |
| US-6586617-B1 | Nontoxic microbiocides such as 4'-chloro-N-ethyl-2'-nitro-p-toluenesulfonanilide, for agricultural or horticultural, prepared by alkylation or nitration | SUMITOMO CHEMICAL TAKEDA AGRO COMPANY, LIMITED (JP) | 2003-07-01 | — | — | US | disclosed |
| EP-1174028-A1 | SULFONAMIDE DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2002-01-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040023938-A1 | Sulfonamide derivatives | FPR1, MRM1, SULT1E1 | UCHL1 3459/4885CES1 275/4885KMT2A 563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.