Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | GALR3 | O60755 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29104740 | 0.82 | TDP1 (0.52) | TDP1TSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL31469524 | 0.80 | TDP1 (0.50) | TDP1TSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL440977 | 0.80 | TDP1 (0.50) | TDP1TSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL13967844 | 0.78 | TDP1 (0.48) | TDP1TSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL6225790 | 0.78 | TDP1 (0.48) | TDP1TSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL7276080 | 0.78 | TDP1 (0.48) | TDP1TSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL1020469 | 0.78 | TDP1 (0.48) | TDP1TSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL425735 | 0.78 | TDP1 (0.48) | TDP1TSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL5200741 | 0.77 | TSHR (0.40) | TDP1TSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL9439802 | 0.77 | ALDH1A1 (0.52) | TDP1TSHRALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0619744-A4 | NONIONIC X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS. | MALLINCKRODT MEDICAL INC (US) | 1995-02-08 | — | — | EP | claimed |
| EP-0619744-A1 | NONIONIC X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS | MALLINCKRODT MEDICAL, INC. (US) | 1994-10-19 | — | — | EP | claimed |
| WO-1994005337-A1 | NONIONIC X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS | MALLINCKRODT MEDICAL, INC. (US) | 1994-03-17 | — | — | WO | claimed |
| WO-1993010825-A1 | NONIONIC X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS | MALLINCKRODT MEDICAL, INC. (US) | 1993-06-10 | — | — | WO | claimed |
| US-5191120-A | Process for preparing nonionic X-ray contrast agents | MALLINCKRODT MEDICAL, INC. (US) | 1993-03-02 | — | — | US | claimed |
| EP-0504266-A1 | NONIONIC X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS | MALLINCKRODT, INC. (US) | 1992-09-23 | — | — | EP | claimed |
| WO-1991009007-A2 | NONIONIC X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS | MALLINCKRODT, INC. (US) | 1991-06-27 | — | — | WO | claimed |
| CN-103113367-A | Preparation method of full-aromaticity beta-carboline compound | UNIV SHIJIAZHUANG | 2013-05-22 | — | — | CN | disclosed |
| US-8124806-B2 | Contrast agents | GE HEALTHCARE AS (NO) | 2012-02-28 | — | — | US | disclosed |
| US-8124806-B2 | Contrast agents | GE HEALTHCARE AS (NO) | 2012-02-28 | — | — | US | disclosed |
| US-8124806-B2 | Contrast agents | GE HEALTHCARE AS (NO) | 2012-02-28 | — | — | US | disclosed |
| EP-1989179-B1 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2011-01-26 | — | — | EP | disclosed |
| EP-1989179-B1 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2011-01-26 | — | — | EP | disclosed |
| WO-2008123779-A1 | TRISUBSTITUTED TRIAZAMACROCYCLI C COMPOUNDS AND THEIR USE AS CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2008-10-16 | — | — | WO | disclosed |
| WO-2007094683-A1 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2007-08-23 | — | — | WO | disclosed |
| WO-2007094683-A1 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2007-08-23 | — | — | WO | disclosed |
| US-5356613-A | X-ray contrast agents, compositions and methods | MALLINCKRODT MEDICAL, INC. (US) | 1994-10-18 | — | — | US | disclosed |
| EP-0558484-A1 | NOVEL X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS | MALLINCKRODT MEDICAL, INC. (US) | 1993-09-08 | — | — | EP | disclosed |
| WO-1992009562-A1 | NOVEL X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS | MALLINCKRODT MEDICAL, INC. (US) | 1992-06-11 | — | — | WO | disclosed |
| US-4001323-A | RADIOPAQUE MATERIALS | SAVAC AG (CH) | 1977-01-04 | — | — | US | disclosed |