Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | PYGM | P11217 | 3/20 | 0.32 |
| ▸ | TK2 | O00142 | 2/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7116224 | 0.82 | LMNA (0.52) | LMNAADRA1AALDH1A1ALBPOLB | |
| SCHEMBL7116228 | 0.82 | LMNA (0.52) | LMNAADRA1AALDH1A1ALBPOLB | |
| SCHEMBL5079292 | 0.81 | LMNA (0.39) | LMNAADRA1AALDH1A1ALBPOLB | |
| SCHEMBL5079307 | 0.81 | LMNA (0.39) | LMNAADRA1AALDH1A1ALBPOLB | |
| SCHEMBL12157191 | 0.80 | LMNA (0.61) | LMNAADRA1AALDH1A1ALBPOLB | |
| SCHEMBL30505858 | 0.80 | LMNA (0.61) | LMNAADRA1AALDH1A1ALBPOLB | |
| SCHEMBL5074429 | 0.80 | ALB (0.39) | LMNAALDH1A1ALBPOLBBLM | |
| SCHEMBL7124525 | 0.79 | BLM (0.63) | LMNAADRA1AALDH1A1ALBPOLB | |
| SCHEMBL7116002 | 0.72 | LMNA (0.43) | LMNAADRA1AALDH1A1ALBBLM | |
| SCHEMBL7115997 | 0.72 | LMNA (0.43) | LMNAADRA1AALDH1A1ALBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1361227-A2 | [5-carboxamide or 5-fluoro]-[2', 3'-unsaturated or 3'-modifield]-pyrimidine nucleosides | Emory University (US) | 2003-11-12 | — | — | EP | claimed |