Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | ALB | P02768 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TK1 | P04183 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7115997 | 1.00 | LMNA (0.43) | LMNAALBALDH1A1MAPK1TK1 | |
| SCHEMBL13065052 | 0.81 | BLM (0.48) | LMNAALBALDH1A1MAPK1TK1 | |
| SCHEMBL7125885 | 0.80 | TK1 (0.39) | LMNATK1TSHRBLMPMP22 | |
| SCHEMBL23485 | 0.80 | LMNA (0.58) | LMNAALBALDH1A1TK1TSHR | |
| SCHEMBL14596607 | 0.80 | LMNA (0.58) | LMNAALBALDH1A1TK1TSHR | |
| SCHEMBL13286394 | 0.80 | LMNA (0.58) | LMNAALBALDH1A1TK1TSHR | |
| SCHEMBL762579 | 0.80 | LMNA (0.58) | LMNAALBALDH1A1TK1TSHR | |
| SCHEMBL19657129 | 0.80 | LMNA (0.48) | LMNAALBALDH1A1MAPK1TK1 | |
| SCHEMBL22992337 | 0.80 | LMNA (0.58) | LMNAALBALDH1A1TK1TSHR | |
| SCHEMBL925743 | 0.80 | LMNA (0.58) | LMNAALBALDH1A1TK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1361227-A2 | [5-carboxamide or 5-fluoro]-[2', 3'-unsaturated or 3'-modifield]-pyrimidine nucleosides | Emory University (US) | 2003-11-12 | — | — | EP | claimed |