Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HMGCR | P04035 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | ACLY | P53396 | 2/20 | 0.36 |
| ▸ | TET2 | Q6N021 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2545818 | 0.78 | TSHR (0.45) | TSHRALDH1A1HMGCRCHRM1TBXA2R | |
| SCHEMBL473141 | 0.78 | TSHR (0.45) | TSHRALDH1A1HMGCRCHRM1TBXA2R | |
| SCHEMBL473138 | 0.78 | TSHR (0.45) | TSHRALDH1A1HMGCRCHRM1TBXA2R | |
| SCHEMBL25634371 | 0.76 | ACLY (0.56) | TSHRALDH1A1HMGCRCHRM1TBXA2R | |
| SCHEMBL2125611 | 0.74 | ACLY (0.37) | TSHRALDH1A1ACLYTET2 | |
| SCHEMBL7367001 | 0.72 | ALDH1A1 (0.40) | TSHRALDH1A1ACLYTET2 | |
| SCHEMBL28695848 | 0.72 | TSHR (0.39) | TSHRALDH1A1HMGCRCHRM1TBXA2R | |
| SCHEMBL2898495 | 0.71 | — | — | |
| SCHEMBL2899117 | 0.71 | — | — | |
| SCHEMBL278725 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1058687-B1 | NUCLEOSIDES | MEDIVIR AB (SE) | 2003-12-10 | — | — | EP | disclosed |