Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7115037 | 0.89 | CHRNA7 (0.38) | SMYD3CHRNA7EZH2TAS1R3TAS1R1 | |
| SCHEMBL7127357 | 0.88 | SMYD3 (0.41) | SMYD3CHRNA7EZH2SLC6A4SLC6A3 | |
| SCHEMBL7116911 | 0.87 | SLC6A2 (0.37) | CHRNA7EZH2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7124891 | 0.86 | CHRNA7 (0.38) | SMYD3CHRNA7EZH2TAS1R3TAS1R1 | |
| SCHEMBL7124224 | 0.85 | CCR2 (0.37) | CHRNA7TAS1R3TAS1R1TAS1R2RIPK2 | |
| SCHEMBL7127540 | 0.85 | EPHX2 (0.40) | CHRNA7SLC6A2SLC6A4SLC6A3NPC1 | |
| SCHEMBL7120754 | 0.84 | CHRNA7 (0.39) | CHRNA7EZH2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7116048 | 0.83 | HPGD (0.46) | CHRNA7EZH2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7125206 | 0.82 | EZH2 (0.41) | SMYD3EZH2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7123867 | 0.82 | CHRNA7 (0.38) | CHRNA7EZH2TAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030069296-A1 | Substituted-aryl 7-aza[2.2.1]bicycloheptanes for the treatment of disease | PHARMACIA & UPJOHN COMPANY | 2003-04-10 | — | — | US | claimed |
| US-20030069296-A1 | Substituted-aryl 7-aza[2.2.1]bicycloheptanes for the treatment of disease | PHARMACIA & UPJOHN COMPANY | 2003-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030069296-A1 | Substituted-aryl 7-aza[2.2.1]bicycloheptanes for the treatment of disease | CYP7B1, UGT2B7, CYP1B1 | SMYD3 4155/4885CHRNA7 397/4885EZH2 462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.