Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7121744 | 0.84 | PDE10A (0.32) | HTR2ACA1CA2EPHX2PDE10A | |
| SCHEMBL6906139 | 0.81 | CA1 (0.33) | HTR2ACA1CA2EPHX2KMT2A | |
| SCHEMBL15272782 | 0.78 | HTR2A (0.38) | HTR2ACA1CA2EPHX2PDE10A | |
| SCHEMBL6912097 | 0.71 | PDK2 (0.39) | HTR2ACA1CA2EPHX2PDE10A | |
| SCHEMBL14062500 | 0.70 | CA1 (0.42) | HTR2ACA1CA2EPHX2KMT2A | |
| SCHEMBL4837456 | 0.69 | PPARG (0.51) | EPHX2KMT2A | |
| SCHEMBL4839883 | 0.68 | EPHX2 (0.43) | HTR2ACA1CA2EPHX2KMT2A | |
| SCHEMBL3485947 | 0.67 | HTR2A (0.42) | HTR2ACA1CA2PDE10AKMT2A | |
| SCHEMBL6067262 | 0.66 | HTR2A (0.33) | HTR2ACA1CA2PDE10A | |
| SCHEMBL6870027 | 0.65 | CA1 (0.46) | HTR2ACA1CA2EPHX2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040106814-A1 | Silicon ether compound, a method for the preparation thereof and use thereof | BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2004-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106814-A1 | Silicon ether compound, a method for the preparation thereof and use thereof | SIK1, CDK20, SGMS1 | HTR2A 4334/4885CA1 960/4885CA2 1464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.