Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 8/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7127706 | 1.00 | LMNA (0.56) | LMNATSHRHPGDKDM4EALDH1A1 | |
| SCHEMBL7124258 | 1.00 | LMNA (0.56) | LMNATSHRHPGDKDM4EALDH1A1 | |
| SCHEMBL6705433 | 0.84 | LMNA (0.55) | LMNATSHRHPGDKDM4EALDH1A1 | |
| SCHEMBL6705432 | 0.84 | LMNA (0.55) | LMNATSHRHPGDKDM4EALDH1A1 | |
| SCHEMBL7119395 | 0.84 | LMNA (0.55) | LMNATSHRHPGDKDM4EALDH1A1 | |
| SCHEMBL20797805 | 0.82 | NPC1 (0.44) | LMNAHPGDKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL5260945 | 0.82 | NPC1 (0.44) | LMNAHPGDKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6626532 | 0.79 | LMNA (0.47) | LMNATSHRHPGDKDM4EALDH1A1 | |
| SCHEMBL2154229 | 0.79 | LMNA (0.47) | LMNATSHRHPGDKDM4EALDH1A1 | |
| SCHEMBL2154230 | 0.79 | LMNA (0.47) | LMNATSHRHPGDKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6660872-B1 | In high yields | BAYER AKTIENGESELLSCHAFT (DE) | 2003-12-09 | — | — | US | disclosed |