Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OAT | P04181 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.32 |
| ▸ | ABAT | P80404 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.32 |
| ▸ | GABRE | P78334 | 1/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.32 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27577694 | 1.00 | OAT (0.47) | OATCES2TSHRLMNAGABRR1 | |
| SCHEMBL11955118 | 1.00 | OAT (0.47) | OATCES2TSHRLMNAGABRR1 | |
| SCHEMBL22487940 | 1.00 | OAT (0.47) | OATCES2TSHRLMNAGABRR1 | |
| SCHEMBL16646284 | 0.79 | OAT (0.44) | OATCES2TSHRLMNAGABRR1 | |
| SCHEMBL7555275 | 0.78 | — | — | |
| SCHEMBL23781995 | 0.77 | — | — | |
| SCHEMBL29615783 | 0.77 | — | — | |
| SCHEMBL21232956 | 0.77 | — | — | |
| SCHEMBL19559700 | 0.76 | CHRM3 (0.36) | TSHRLMNABLM | |
| SCHEMBL24240596 | 0.71 | CES2 (0.38) | OATCES2TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6670168-B1 | Cell comprises a modified rapamycin polyketide synthase (PKS) gene cluster with an acyltransferase (AT) domain in extender module 10 having malonyl CoA specificity. | KOSAN BIOSCIENCE, INC. | 2003-12-30 | — | — | US | disclosed |