Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 13/20 | 0.70 |
| ▸ | ESR2 | Q92731 | 12/20 | 0.70 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.70 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | AR | P10275 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | ESRRG | P62508 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SHBG | P04278 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4905749 | 0.87 | ESR1 (0.70) | ESR1ESR2PDCD1CD274CYP3A4 | |
| SCHEMBL12721606 | 0.87 | ESR1 (0.70) | ESR1ESR2PDCD1CD274CYP3A4 | |
| SCHEMBL7919913 | 0.87 | ESR1 (0.70) | ESR1ESR2PDCD1CD274CYP3A4 | |
| SCHEMBL7917275 | 0.87 | ESR1 (0.59) | ESR1ESR2PDCD1CD274CYP3A4 | |
| SCHEMBL9808290 | 0.86 | ESR1 (0.55) | ESR1ESR2PDCD1CD274CYP3A4 | |
| SCHEMBL7593822 | 0.84 | ESR1 (0.61) | ESR1ESR2PDCD1CD274CYP3A4 | |
| SCHEMBL26946 | 0.83 | ESR1 (1.00) | ESR1ESR2PDCD1CD274CYP3A4 | |
| SCHEMBL10593295 | 0.83 | ESR1 (1.00) | ESR1ESR2PDCD1CD274CYP3A4 | |
| SCHEMBL22335854 | 0.83 | ESR1 (0.80) | ESR1ESR2CYP3A4LMNAAR | |
| SCHEMBL18750 | 0.83 | ESR1 (0.80) | ESR1ESR2CYP3A4LMNAAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030165772-A1 | Negative resist composition | FUJI PHOTO FILM CO., LTD. | 2003-09-04 | — | — | US | disclosed |
| WO-2002097806-A1 | POLYCARBONATES FOR OPTICAL USE, AND THEIR APPLICATIONS | GENERAL ELECTRIC COMPANY (US) | 2002-12-05 | — | — | WO | disclosed |
| US-4985393-A | Bis/hydroxyphenylthio/ Compounds | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |