Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 10/20 | 0.57 |
| ▸ | MERTK | Q12866 | 3/20 | 0.54 |
| ▸ | ULK1 | O75385 | 1/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8900449 | 0.81 | NPY5R (0.81) | NPY5RMERTKULK1SLC2A1KDM1A | |
| SCHEMBL7117730 | 0.80 | AURKA (0.47) | NPY5RMERTKNPC1RAB9APIN1 | |
| SCHEMBL2591063 | 0.75 | NPY5R (1.00) | NPY5RMERTKSLC2A1NPC1TP53 | |
| SCHEMBL4485558 | 0.74 | MOK (0.44) | NPY5RMERTKSLC2A1MAPK1SMN1; SMN2 | |
| SCHEMBL2590203 | 0.74 | NPY5R (0.97) | NPY5RMERTKSLC2A1KDM1ATP53 | |
| Hydrochloric Acid SCHEMBL6039677 | 0.73 | NPY5R (0.96) | NPY5RSLC2A1NPC1TP53PKM | |
| SCHEMBL8890945 | 0.73 | NPY5R (1.00) | NPY5RSLC2A1KDM1ATP53MAPK1 | |
| SCHEMBL13794057 | 0.73 | NPC1 (0.69) | NPY5RMERTKULK1SLC2A1KDM1A | |
| Hydrochloric Acid SCHEMBL8900357 | 0.72 | NPY5R (0.97) | NPY5RSLC2A1NPC1TP53MAPK1 | |
| SCHEMBL12430732 | 0.71 | AURKA (0.84) | NPY5RULK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030078275-A1 | Pyrazole compounds useful as protein kinase inhibitors | VERTEX PHARMACEUTICALS INCORPORATED | 2003-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030078275-A1 | Pyrazole compounds useful as protein kinase inhibitors | AURKC, AURKA, GSK3B | NPY5R 1263/4885MERTK 1439/4885ULK1 612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.