Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 9/20 | 1.00 |
| ▸ | PGK1 | P00558 | 1/20 | 0.69 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.67 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.62 |
| ▸ | AURKA | O14965 | 1/20 | 0.61 |
| ▸ | SRC | P12931 | 1/20 | 0.61 |
| ▸ | GSK3B | P49841 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | XBP1 | P17861 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8900357 | 0.98 | NPY5R (0.97) | NPY5RPGK1SLC2A1MAPTLMNA | |
| SCHEMBL2590203 | 0.98 | NPY5R (0.97) | NPY5RPGK1SLC2A1MAPTLMNA | |
| SCHEMBL2591063 | 0.90 | NPY5R (1.00) | NPY5RSLC2A1TP53ABCG2AURKA | |
| Hydrochloric Acid SCHEMBL6039677 | 0.89 | NPY5R (0.96) | NPY5RSLC2A1MAPTTP53ABCG2 | |
| SCHEMBL2592190 | 0.88 | NPY5R (0.78) | NPY5RPGK1SLC2A1MAPTLMNA | |
| SCHEMBL8901062 | 0.86 | NPY5R (0.84) | NPY5RSLC2A1LMNAABCG2ALDH1A1 | |
| SCHEMBL8898077 | 0.86 | NPY5R (0.84) | NPY5RSLC2A1MAPTABCG2KDM4E | |
| Hydrochloric Acid SCHEMBL8898758 | 0.84 | NPY5R (0.81) | NPY5RSLC2A1MAPTABCG2KDM4E | |
| SCHEMBL8890555 | 0.84 | NPY5R (1.00) | NPY5RSLC2A1MAPTTP53ABCG2 | |
| Hydrochloric Acid SCHEMBL8900034 | 0.84 | NPY5R (0.81) | NPY5RSLC2A1LMNATP53ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020822-A1 | QUINAZOLIN-2,4-DIAZIRINES AS NPY RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |