Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 12/20 | 0.61 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.41 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.41 |
| ▸ | CTSV | O60911 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7121640 | 0.84 | TNFRSF1A (0.64) | TNFRSF1ANPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL7090129 | 0.77 | TNFRSF1A (0.55) | TNFRSF1A | |
| SCHEMBL5575701 | 0.76 | TNFRSF1A (1.00) | TNFRSF1A | |
| SCHEMBL5575695 | 0.76 | TNFRSF1A (1.00) | TNFRSF1A | |
| SCHEMBL7087083 | 0.75 | TNFRSF1A (0.54) | TNFRSF1A | |
| SCHEMBL6986840 | 0.74 | TNFRSF1A (0.65) | TNFRSF1AHPGD | |
| SCHEMBL6092023 | 0.73 | TNFRSF1A (0.55) | TNFRSF1A | |
| SCHEMBL7087566 | 0.71 | TNFRSF1A (0.55) | TNFRSF1A | |
| SCHEMBL6091965 | 0.70 | TNFRSF1A (0.52) | TNFRSF1A | |
| SCHEMBL6040654 | 0.70 | TNFRSF1A (0.52) | TNFRSF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003033662-A2 | PROTECTION AGAINST OXIDATIVE STRESS AND INFLAMMATION BY A CYTOPROTECTIVE RESPONSE ELEMENT | ATHEROGENICS, INC. (US) | 2003-04-24 | — | — | WO | disclosed |