SCHEMBL7124940

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7122490	0.87	HSD17B10 (0.62)	HSD17B10TSHRRAB9AALDH1A1PDE9A
	SCHEMBL7116744	0.86	SIRT1 (0.46)	HSD17B10TSHRRAB9AALDH1A1PDE9A
	SCHEMBL7119334	0.86	HSD17B10 (0.45)	HSD17B10TSHRRAB9AALDH1A1PDE9A
	SCHEMBL7117392	0.85	HSD17B10 (0.48)	HSD17B10TSHRRXFP1ALDH1A1HPGD
	SCHEMBL7124010	0.85	SIRT1 (0.45)	HSD17B10TSHRRAB9AALDH1A1PDE9A
	SCHEMBL7114914	0.83	SIRT1 (0.46)	HSD17B10TSHRNPSR1RAB9AALDH1A1
	SCHEMBL7119105	0.83	MEN1 (0.53)	HSD17B10TSHRRAB9AALDH1A1PDE9A
	SCHEMBL7114098	0.83	PDE9A (0.58)	HSD17B10TSHRCYP1A2CYP2C19RAB9A
	SCHEMBL7125625	0.81	KDM4E (0.43)	HSD17B10TSHRNPSR1RAB9AALDH1A1
	SCHEMBL7552947	0.79	SIRT1 (0.40)	HSD17B10TSHRRAB9AALDH1A1PDE9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.