SCHEMBL712495

SCHEMBL712495

C=CC(=O)Nc1ccc(OC(=O)C=Cc2ccc(OC)cc2)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 1/20 0.71
MAPT P10636 6/20 0.64
MMP1 P03956 4/20 0.64
MMP2 P08253 4/20 0.64
MMP9 P14780 4/20 0.64
TP53 P04637 3/20 0.64
SMN1; SMN2 Q16637 2/20 0.64
THRB P10828 1/20 0.64
MEN1 O00255 2/20 0.62
KMT2A Q03164 2/20 0.62
LMNA P02545 2/20 0.62
CYP3A4 P08684 1/20 0.62
CYP2D6 P10635 1/20 0.62
PKM P14618 1/20 0.62
TSHR P16473 1/20 0.62
NFKB1 P19838 1/20 0.62
MAPK1 P28482 1/20 0.62
CYP2C19 P33261 1/20 0.62
THPO P40225 1/20 0.62
NPC1 O15118 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10015758 0.90 MAPT (0.71) TGM2MAPTMMP1MMP2MMP9
SCHEMBL14275350 0.86 TGM2 (0.62) TGM2MMP1MMP2MMP9KMT2A
SCHEMBL28593818 0.86 F3 (0.69) TGM2MAPTMMP1MMP2MMP9
SCHEMBL28593816 0.86 F3 (0.69) TGM2MAPTMMP1MMP2MMP9
SCHEMBL14275338 0.84 KMT2A (0.66) MAPTTHRBMEN1KMT2ALMNA
SCHEMBL15164043 0.84 KMT2A (0.66) MAPTTHRBMEN1KMT2ALMNA
SCHEMBL782552 0.84 TGM2 (1.00) TGM2MAPTMMP1MMP2MMP9
SCHEMBL711114 0.83 MAPT (0.55) MAPTMMP1MMP2MMP9TP53
SCHEMBL17693073 0.83 MAPT (0.88) MAPTMMP1MMP2MMP9TP53
SCHEMBL18121572 0.83 KMT2A (0.76) MAPTTHRBMEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1945737-B1 COPOLYMER FOR LIQUID CRYSTAL ALIGNMENT, LIQUID CRYSTAL ALIGNING LAYER INCLUDING COPOLYMER FOR LIQUID CRYSTAL ALIGNMENT, AND LIQUID CRYSTAL DISPLAY INCLUDING LIQUID CRYSTAL ALIGNING LAYER LG CHEMICAL LTD (KR) 2013-03-06 EP disclosed
US-8123977-B2 Copolymer for liquid crystal alignment, liquid crystal aligning layer including copolymer for liquid crystal alignment, and liquid crystal display including liquid crystal aligning layer LG CHEM, LTD. (KR) 2012-02-28 US disclosed
EP-1945737-A1 COPOLYMER FOR LIQUID CRYSTAL ALIGNMENT, LIQUID CRYSTAL ALIGNING LAYER INCLUDING COPOLYMER FOR LIQUID CRYSTAL ALIGNMENT, AND LIQUID CRYSTAL DISPLAY INCLUDING LIQUID CRYSTAL ALIGNING LAYER LG Chem, Ltd. (KR) 2008-07-23 EP disclosed
WO-2007052979-A1 COPOLYMER FOR LIQUID CRYSTAL ALIGNMENT, LIQUID CRYSTAL ALIGNING LAYER INCLUDING COPOLYMER FOR LIQUID CRYSTAL ALIGNMENT, AND LIQUID CRYSTAL DISPLAY INCLUDING LIQUID CRYSTAL ALIGNING LAYER LG CHEM. LTD. (KR) 2007-05-10 WO disclosed
US-20070102668-A1 Copolymer for liquid crystal alignment , liquid crystal aligning layer including copolymer for liquid crystal alignment, and liquid crystal display including liquid crystal aligning layer LG CHEM, LTD. (KR) 2007-05-10 US disclosed