SCHEMBL782552

SCHEMBL782552

C=CC(=O)Nc1ccc(OC)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 7/20 1.00
SMN1; SMN2 Q16637 4/20 0.63
NPC1 O15118 3/20 0.63
RAB9A P51151 3/20 0.63
LMNA P02545 2/20 0.59
F13A1 P00488 1/20 0.59
TGM1 P22735 1/20 0.59
TGM3 Q08188 1/20 0.59
MMP1 P03956 2/20 0.58
MMP2 P08253 2/20 0.58
MMP9 P14780 2/20 0.58
EGFR P00533 1/20 0.58
TP53 P04637 3/20 0.58
ALOX15 P16050 1/20 0.58
MAPT P10636 2/20 0.56
THRB P10828 1/20 0.56
POLB P06746 1/20 0.56
CYP3A4 P08684 1/20 0.55
CYP2D6 P10635 1/20 0.55
PKM P14618 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8467427 0.95 TGM2 (0.90) TGM2SMN1; SMN2NPC1RAB9ALMNA
SCHEMBL20456547 0.95 TGM2 (0.90) TGM2SMN1; SMN2NPC1RAB9ALMNA
SCHEMBL15709186 0.85 TGM2 (0.73) TGM2SMN1; SMN2NPC1RAB9ALMNA
SCHEMBL14341775 0.85 TGM2 (0.86) TGM2SMN1; SMN2LMNAF13A1TGM1
SCHEMBL15709188 0.85 TGM2 (0.73) TGM2SMN1; SMN2NPC1RAB9ALMNA
SCHEMBL712495 0.84 TGM2 (0.71) TGM2SMN1; SMN2NPC1RAB9ALMNA
SCHEMBL439369 0.84 TGM2 (0.79) TGM2LMNAF13A1TGM1TGM3
SCHEMBL8151744 0.83 MTNR1B (0.74) TGM2SMN1; SMN2POLBALDH1A1
SCHEMBL28593816 0.83 F3 (0.69) TGM2SMN1; SMN2NPC1RAB9ALMNA
SCHEMBL28593818 0.83 F3 (0.69) TGM2SMN1; SMN2NPC1RAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118955381-A Pyrazole compound as well as preparation method and application thereof 赣南师范大学 2024-11-15 CN claimed
CN-117466789-A Synthesis method of beta-trifluoromethylthioamide participated by silver trifluormethane 陕西先氟领创科技有限公司 2024-01-30 CN claimed
JP-4828407-B2 2011-11-30 JP claimed
EP-1229057-B1 Organosol and liquid inks comprising the same SAMSUNG ELECTRONICS CO LTD (KR) 2007-05-23 EP claimed
CN-1234785-C Liquid ink containing surface treatment coloring agent particle and productive method thereof SAMSUNG ELECTRONICS CO LTD (KR) 2006-01-04 CN claimed
EP-1594869-A2 3-SUBSTITUTED-2(ARYLALKYL)-1-AZABICYCLOALKANES AND METHODS OF USE THEREOF Targacept, Inc. (US) 2005-11-16 EP claimed
CN-1222560-C Organic sol and printing ink containing said organic sol SAMSUNG ELECTRONICS CO LTD (KR) 2005-10-12 CN claimed
US-20050009952-A1 Liquid inks comprising a stable organosol SAMSUNG ELECTRONICS CO. LTD. 2005-01-13 US claimed
WO-2004076449-A2 3-SUBSTITUTED-2(ARYLALKYL)-1-AZABICYCLOALKANES AND METHODS OF USE THEREOF TARGACEPT, INC. (US) 2004-09-10 WO claimed
US-20020128349-A1 Liquid inks comprising a stable organosol S-PRINTING SOLUTION CO., LTD. (KR) 2002-09-12 US claimed
CN-1367194-A Organic sol and printing ink containing said organic sol SAMSUNG ELECTRONICS CO LTD (KR) 2002-09-04 CN claimed
EP-1229057-A2 Organosol and liquid inks comprising the same Samsung Electronics Co., Ltd. (KR) 2002-08-07 EP claimed
CN-1358807-A Liquid ink containing surface treatment coloring agent particle and productive method thereof SAMSUNG ELECTRONICS CO LTD (KR) 2002-07-17 CN claimed
EP-1205815-A1 Liquid inks comprising surface-treated colorant particles and manufacturing method thereof Samsung Electronics Co., Ltd. (KR) 2002-05-15 EP claimed
CN-87101979-A diphenylmethane derivatives and pharmaceutical use 1987-10-28 CN claimed
US-20260146122-A1 POLYMERS MOLECULAR MEDICAL LTD (GB) 2026-05-28 US disclosed
EP-4594380-A1 POLYMERS Molecular Medical Ltd (GB) 2025-08-06 EP disclosed
US-4288620-A FROM P-ALKOXYANILINES; NITRATION IN PRESENCE OF SULFURIC ACID CIBA-GEIGY AG (CH) 1981-09-08 US disclosed
EP-0001997-B1 ELECTRON BEAM-CURABLE PHOTORESIST LACQUERS BAYER AG (DE) 1981-02-11 EP disclosed
EP-0001997-A1 Electron beam-curable photoresist lacquers BAYER AG (DE) 1979-05-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260146122-A1 POLYMERS FGB, IPMK, PFKP TGM2 3308/4885SMN1; SMN2 1208/4885NPC1 4184/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.