Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7130146 | 0.92 | THRB (0.39) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL1697075 | 0.84 | THRB (0.36) | TSHRTHRBALDH1A1 | |
| SCHEMBL10150627 | 0.82 | TSHR (0.38) | TSHRTHRBALDH1A1 | |
| SCHEMBL7132594 | 0.81 | TSHR (0.41) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL12153658 | 0.81 | TSHR (0.37) | TSHRTHRBALDH1A1SMN1; SMN2 | |
| SCHEMBL4197538 | 0.76 | TSHR (0.44) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL7131323 | 0.76 | ALDH1A1 (0.31) | TSHRALDH1A1 | |
| SCHEMBL12153629 | 0.76 | THRB (0.36) | TSHRTHRBALDH1A1 | |
| SCHEMBL7125369 | 0.76 | TSHR (0.44) | TSHRALDH1A1 | |
| SCHEMBL685715 | 0.75 | TSHR (0.33) | TSHRTHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6670499-B1 | Bis-Methacryloyloxy-adamantanedicarboxylate derivatives; raw materials for dental materials and lenses; transparency, luster, hardness, water resistance | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2003-12-30 | — | — | US | disclosed |
| EP-1164125-A1 | ADAMANTANE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Daicel Chemical Industries, Ltd. (JP) | 2001-12-19 | — | — | EP | disclosed |