Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 15/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.34 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7117129 | 0.87 | CHRNA7 (0.37) | CHRNA7TAS1R3TAS1R1TAS1R2EZH2 | |
| SCHEMBL7125259 | 0.87 | NSD2 (0.41) | PIK3C3CHRNA7EZH2 | |
| SCHEMBL7123867 | 0.86 | CHRNA7 (0.38) | CHRNA7TAS1R3TAS1R1TAS1R2EZH2 | |
| SCHEMBL7122575 | 0.84 | TAS1R3 (0.43) | CHRNA7TAS1R3TAS1R1TAS1R2EZH2 | |
| SCHEMBL7126672 | 0.84 | CHRNA7 (0.35) | PIK3C3CHRNA7BRAFTAS1R3TAS1R1 | |
| SCHEMBL7117116 | 0.84 | CHRNA7 (0.42) | CHRNA7EZH2 | |
| SCHEMBL7126739 | 0.84 | EGLN1 (0.39) | CHRNA7 | |
| SCHEMBL7123911 | 0.83 | MAPK14 (0.43) | PIK3C3BRAF | |
| SCHEMBL7116046 | 0.83 | CHRNA7 (0.43) | CHRNA7EZH2 | |
| SCHEMBL7119268 | 0.82 | CTSC (0.38) | CHRNA7TAS1R3TAS1R1TAS1R2EZH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030069296-A1 | Substituted-aryl 7-aza[2.2.1]bicycloheptanes for the treatment of disease | PHARMACIA & UPJOHN COMPANY | 2003-04-10 | — | — | US | claimed |
| US-20030069296-A1 | Substituted-aryl 7-aza[2.2.1]bicycloheptanes for the treatment of disease | PHARMACIA & UPJOHN COMPANY | 2003-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030069296-A1 | Substituted-aryl 7-aza[2.2.1]bicycloheptanes for the treatment of disease | CYP7B1, UGT2B7, CYP1B1 | PIK3C3 809/4885CHRNA7 397/4885BRAF 3842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.