Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6673711 | 0.74 | ALDH1A1 (1.00) | ALDH1A1KDM4EMAPTTSHRSMN1; SMN2 | |
| SCHEMBL6670041 | 0.74 | ALDH1A1 (0.55) | ALDH1A1KDM4EGAATSHRSMN1; SMN2 | |
| SCHEMBL14369638 | 0.73 | KDM4E (0.68) | ALDH1A1KDM4EGAAMAPTSMN1; SMN2 | |
| SCHEMBL3945483 | 0.72 | ALDH1A1 (0.58) | ALDH1A1KDM4EGAATSHRSMN1; SMN2 | |
| SCHEMBL5009981 | 0.71 | ALDH1A1 (0.56) | ALDH1A1KDM4EGAAMAPTSMN1; SMN2 | |
| SCHEMBL4532269 | 0.71 | ALDH1A1 (0.51) | ALDH1A1KDM4EGAAMAPTSMN1; SMN2 | |
| SCHEMBL15005226 | 0.71 | MAPT (1.00) | ALDH1A1KDM4EGAAMAPTTSHR | |
| SCHEMBL24157593 | 0.70 | ALDH1A1 (0.49) | ALDH1A1KDM4EGAAMAPTTSHR | |
| SCHEMBL17426082 | 0.70 | KDM4E (0.63) | ALDH1A1KDM4EGAAMAPTTSHR | |
| SCHEMBL7834913 | 0.70 | KDM4E (0.51) | ALDH1A1KDM4EHPGDLMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030096813-A1 | Compositions useful as inhibitors of GSK-3 | CAO JINGRONG (US) | 2003-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030096813-A1 | Compositions useful as inhibitors of GSK-3 | GSK3B, GSK3A, GSKIP | ALDH1A1 3164/4885KDM4E 1667/4885GAA 3518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.