Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 3/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1490146 | 0.84 | LMNA (0.41) | TAAR1AOC3NPC1LMNATP53 | |
| SCHEMBL16316809 | 0.79 | LMNA (0.38) | TAAR1AOC3NPC1LMNATP53 | |
| SCHEMBL6883380 | 0.78 | TSHR (0.41) | AOC3NPC1LMNAMAPTNFKB1 | |
| SCHEMBL9281558 | 0.77 | ESR1 (0.40) | TAAR1AOC3MAPTESR1MEN1 | |
| SCHEMBL7612924 | 0.75 | TAAR1 (0.35) | TAAR1SMN1; SMN2MC4RESR1PER2 | |
| SCHEMBL10989336 | 0.74 | ESR1 (0.40) | TAAR1AOC3NPC1LMNATP53 | |
| SCHEMBL10620529 | 0.72 | ESR1 (0.47) | TAAR1AOC3TP53MAPTESR1 | |
| SCHEMBL8959927 | 0.72 | TSHR (0.55) | TAAR1AOC3NPC1MAPTRAB9A | |
| SCHEMBL24620291 | 0.71 | KDM4E (0.40) | TAAR1SLC6A2SLC6A3AOC3NPC1 | |
| SCHEMBL10989335 | 0.70 | TAAR1 (0.43) | TAAR1AOC3NPC1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6669765-B2 | Thermochromic dry offset ink, and printed article produced using the same | THE PILOT INK CO., LTD. (JP) | 2003-12-30 | — | — | US | disclosed |
| US-20020121218-A1 | Thermochromic dry offset ink, and printed article produced using the same | PILOT INK CO., LTD., THE (JP) | 2002-09-05 | — | — | US | disclosed |
| EP-0787779-B1 | Preparation method for shear-thinning water-based ball-point pen inks, shear-thinning water-based ball-point pen ink compositions, and ball-point pens employing the same | PILOT INK CO LTD (JP) | 2001-07-18 | — | — | EP | disclosed |
| US-5785746-A | INKS WITH COLOR, SOLVENT, NONIONIC SURFACTANT FOR BALL POINT PENS | THE PILOT INK CO., LTD. (JP) | 1998-07-28 | — | — | US | disclosed |
| EP-0665119-B1 | Thermochromic colour-memory composition | PILOT INK CO LTD (JP) | 1997-12-03 | — | — | EP | disclosed |
| EP-0787779-A2 | Preparation method for shear-thinning water-based ball-point pen inks, shear-thinning water-based ball-point pen ink compositions, and ball-point pens employing the same | The Pilot Ink CO., Ltd. (JP) | 1997-08-06 | — | — | EP | disclosed |
| US-5558699-A | COLOR IS RETAINED AFTER HEATING OR COOLING IS WITHDRAWN, REACTION MEDIUM IS ALKYL OR ALKYLARYL KETONE | THE PILOT INK CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |
| EP-0665119-A1 | Thermochromic colour-memory composition | THE PILOT INK CO., LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |