Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16316809 | 0.89 | LMNA (0.38) | LMNANPC1TP53MAPTNFKB1 | |
| SCHEMBL10989336 | 0.84 | ESR1 (0.40) | LMNANPC1TP53MAPTNFKB1 | |
| SCHEMBL7125671 | 0.84 | TAAR1 (0.37) | LMNANPC1TP53MAPTNFKB1 | |
| SCHEMBL10620529 | 0.82 | ESR1 (0.47) | TP53MAPTESR1ACHEKMT2A | |
| SCHEMBL6299189 | 0.82 | TSHR (0.46) | LMNANPC1TP53MAPTRAB9A | |
| SCHEMBL31718395 | 0.82 | TSHR (0.46) | LMNANPC1TP53MAPTRAB9A | |
| SCHEMBL24620291 | 0.81 | KDM4E (0.40) | LMNANPC1TP53MAPTNFKB1 | |
| SCHEMBL8446375 | 0.79 | TAAR1 (0.41) | LMNANPC1TP53MAPTNFKB1 | |
| SCHEMBL10625468 | 0.79 | LMNA (0.43) | LMNASMN1; SMN2KDM4EESR1MEN1 | |
| SCHEMBL4752048 | 0.77 | KDM4E (0.38) | LMNANPC1TP53MAPTNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6238226-A | — | — | None | — | — | JP | disclosed |
| EP-4446310-A1 | METHOD FOR PRODUCING BLOCKED ISOCYANATE COMPOUND AND METHOD FOR PRODUCING ISOCYANATE COMPOUND | Asahi Kasei Kabushiki Kaisha (JP) | 2024-10-16 | — | — | EP | disclosed |
| WO-2023189803-A1 | RESIST UNDERLAYER FILM FORMING COMPOSITION | 日産化学株式会社 | 2023-10-05 | — | — | WO | disclosed |
| WO-2023189799-A1 | SELF CROSS-LINKABLE POLYMER AND RESIST UNDERLAYER FILM-FORMING COMPOSITION | 日産化学株式会社 | 2023-10-05 | — | — | WO | disclosed |
| WO-2023106377-A1 | METHOD FOR PRODUCING BLOCKED ISOCYANATE COMPOUND AND METHOD FOR PRODUCING ISOCYANATE COMPOUND | 旭化成株式会社 | 2023-06-15 | — | — | WO | disclosed |
| US-20230131253-A1 | RESIST UNDERLAYER FILM-FORMING COMPOSITION WITH SUPPRESSED DEGENERATION OF CROSSLINKING AGENT | NISSAN CHEMICAL CORPORATION (JP) | 2023-04-27 | — | — | US | disclosed |
| US-20230131253-A1 | RESIST UNDERLAYER FILM-FORMING COMPOSITION WITH SUPPRESSED DEGENERATION OF CROSSLINKING AGENT | NISSAN CHEMICAL CORPORATION (JP) | 2023-04-27 | — | — | US | disclosed |
| US-8530379-B2 | Thermosensitive recording material and production method thereof | RICOH COMPANY, LTD. (JP) | 2013-09-10 | — | — | US | disclosed |
| EP-2295257-B1 | Thermosensitive recording material and production method thereof | RICOH CO LTD (JP) | 2012-08-29 | — | — | EP | disclosed |
| US-20110065575-A1 | THERMOSENSITIVE RECORDING MATERIAL AND PRODUCTION METHOD THEREOF | RICOH COMPANY, LTD. (JP) | 2011-03-17 | — | — | US | disclosed |
| EP-2295257-A1 | Thermosensitive recording material and production method thereof | Ricoh Company, Ltd. (JP) | 2011-03-16 | — | — | EP | disclosed |
| US-20100228026-A1 | NOVEL MALONIC ACID SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2010-09-09 | — | — | US | disclosed |
| CN-100439324-C | One-step method for preparing N-alkyl aromatic amine from aromatic nitro substance | ZHEJIANG POLYTECHNIQUE UNIV (CN) | 2008-12-03 | — | — | CN | disclosed |
| CN-1814582-A | One-step method for preparing N-alkyl aromatic amine from aromatic nitro substance | ZHEJIANG POLYTECHNIQUE UNIV (CN) | 2006-08-09 | — | — | CN | disclosed |
| CN-1079814-C | Writing instrument | KAWASHIMA KIYOHARU (JP) | 2002-02-27 | — | — | CN | disclosed |
| JP-H06238226-A | PEN SET | KAWASHIMA SEIJI | 1994-08-30 | — | — | JP | disclosed |
| US-4746756-A | Photoconductive imaging members with novel fluorinated squaraine compounds | XEROX CORPORATION (US) | 1988-05-24 | — | — | US | disclosed |
| US-4621038-A | Photoconductive imaging members with novel symmetrical fluorinated squaraine compounds | XEROX CORPORATION (US) | 1986-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100228026-A1 | NOVEL MALONIC ACID SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | REN, AGTR2, AGTR1 | LMNA 3803/4885NPC1 3306/4885TP53 3377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.