Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 20/20 | 0.73 |
| ▸ | CTSS | P25774 | 17/20 | 0.73 |
| ▸ | CTSL | P07711 | 14/20 | 0.73 |
| ▸ | CTSB | P07858 | 11/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4714963 | 0.95 | CTSK (0.76) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4718649 | 0.90 | CTSK (0.71) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4714408 | 0.85 | CTSK (0.74) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4716413 | 0.85 | CTSK (0.66) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4712035 | 0.84 | CTSK (1.00) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4713424 | 0.84 | CTSK (0.89) | CTSKCTSSCTSLCTSB | |
| SCHEMBL6215427 | 0.84 | CTSK (0.89) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4715874 | 0.84 | CTSS (0.75) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4712307 | 0.82 | CTSK (0.68) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4712461 | 0.82 | CTSK (0.78) | CTSKCTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6525036-B2 | Treating post-menopausal osteoporosis. | MERCK & CO., INC. | 2003-02-25 | — | — | US | disclosed |