Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 7/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5751816 | 1.00 | CETP (0.40) | CETPTAAR1SLC7A5HTR2AHTR2C | |
| SCHEMBL5752731 | 0.89 | CETP (0.46) | CETP | |
| SCHEMBL5749572 | 0.87 | CETP (0.48) | CETP | |
| SCHEMBL5750291 | 0.84 | TAAR1 (0.43) | CETPTAAR1 | |
| SCHEMBL5750654 | 0.82 | CETP (0.43) | CETP | |
| SCHEMBL5749740 | 0.82 | SLC1A1 (0.43) | CETPSLC7A5 | |
| SCHEMBL5752681 | 0.82 | CYP17A1 (0.44) | CETPTAAR1HTR2AHTR2CHTR2B | |
| SCHEMBL5750636 | 0.80 | HTR2A (0.47) | CETPHTR2AHTR2CHTR2B | |
| SCHEMBL5753859 | 0.79 | HTR1A (0.46) | CETPTAAR1HTR2AHTR2C | |
| SCHEMBL5752561 | 0.78 | ADRA2A (0.40) | HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362846-A1 | AMINOETHANOL DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2003-11-19 | — | — | EP | disclosed |