Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2B6 | P20813 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5816021 | 0.89 | CYP2B6 (0.43) | CYP2B6CHRM3CHRM2CHRM1CYP2D6 | |
| SCHEMBL18112743 | 0.87 | CYP2B6 (0.41) | CYP2B6CHRM3CHRM2CHRM1CYP2D6 | |
| SCHEMBL2127685 | 0.85 | CYP2B6 (0.50) | CYP2B6CHRM3CHRM2CHRM1CYP2D6 | |
| SCHEMBL2128439 | 0.85 | CYP2B6 (0.50) | CYP2B6CHRM3CHRM2CHRM1CYP2D6 | |
| SCHEMBL327106 | 0.84 | CYP2B6 (0.45) | CYP2B6CHRM3CHRM2CHRM1CYP2D6 | |
| SCHEMBL4901870 | 0.80 | CYP2B6 (0.45) | CYP2B6CHRM3CHRM2CHRM1CYP2D6 | |
| SCHEMBL703097 | 0.77 | CYP2B6 (0.44) | CYP2B6CHRM3CHRM2CHRM1CYP2D6 | |
| SCHEMBL7965625 | 0.76 | NPC1 (0.43) | CYP2B6CHRM3CYP2D6KDM4ELMNA | |
| SCHEMBL14476967 | 0.75 | CHRM3 (0.41) | CYP2B6CHRM3CHRM2CHRM1CYP2D6 | |
| SCHEMBL30607042 | 0.74 | SLC6A2 (0.43) | CYP2B6CHRM3KCNH2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043922-A8 | METHOD OF PREPARATION OF TERFENADINE AND ITS DERIVATIVES | ZENTIVA AS (SK) | 2004-09-10 | — | — | WO | disclosed |
| WO-2004043922-A1 | METHOD OF PREPARATION OF TERFENADINE AND ITS DERIVATIVES | ZENTIVA, A.S. (SK) | 2004-05-27 | — | — | WO | disclosed |
| WO-2004043922-A1 | METHOD OF PREPARATION OF TERFENADINE AND ITS DERIVATIVES | ZENTIVA, A.S. (SK) | 2004-05-27 | — | — | WO | disclosed |