Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 7/20 | 0.60 |
| ▸ | NOS1 | P29475 | 7/20 | 0.60 |
| ▸ | NOS2 | P35228 | 7/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7126075 | 0.88 | NOS3 (0.79) | NOS3NOS1NOS2MAPTMEN1 | |
| SCHEMBL5833752 | 0.82 | NOS3 (0.74) | NOS3NOS1NOS2MAPTMEN1 | |
| SCHEMBL5833909 | 0.77 | NOS3 (0.98) | NOS3NOS1NOS2HRH3HTR2A | |
| SCHEMBL7409113 | 0.76 | NOS3 (0.75) | NOS3NOS1NOS2HRH3HTR2A | |
| SCHEMBL5834017 | 0.76 | NOS3 (1.00) | NOS3NOS1NOS2HRH3HTR2A | |
| SCHEMBL7188765 | 0.74 | MEN1 (0.46) | MAPTMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL5833404 | 0.72 | NOS3 (0.76) | NOS3NOS1NOS2MAPTMEN1 | |
| SCHEMBL5833630 | 0.72 | NOS3 (0.69) | NOS3NOS1NOS2MAPTKDM4E | |
| SCHEMBL7083997 | 0.71 | NOS3 (0.85) | NOS3NOS1NOS2HRH3HTR2A | |
| SCHEMBL5833244 | 0.71 | NOS3 (0.64) | NOS3NOS1NOS2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003523941-A | — | — | 2003-08-12 | — | — | JP | claimed |
| EP-1178784-A1 | NEW PHARMACEUTICAL COMBINATIONS FOR NOS INHIBITORS | Pfizer Products Inc. (US) | 2002-02-13 | — | — | EP | claimed |
| WO-2000071107-A2 | NEW PHARMACEUTICAL COMBINATIONS FOR NOS INHIBITORS | PFIZER PRODUCTS INC. (US) | 2000-11-30 | — | — | WO | claimed |