SCHEMBL7126133

SCHEMBL7126133

C=C(C)C(=O)OC(C)CC(=O)OC12CC3CC(C1)CC(OC(=O)CC(C)OC(=O)C(=C)C)(C3)C2

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.32
TSHR P16473 2/20 0.32
ALDH1A1 P00352 1/20 0.30
EPHX2 P34913 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7129769 0.83 TSHR (0.42) CYP19A1TSHRALDH1A1
SCHEMBL7130970 0.82 TSHR (0.33) TSHR
SCHEMBL737596 0.79 ALDH1A1 (0.35) CYP19A1TSHRALDH1A1
SCHEMBL12777555 0.78 CYP19A1 (0.33) CYP19A1TSHRALDH1A1EPHX2
SCHEMBL14054282 0.78 CYP19A1 (0.33) CYP19A1TSHRALDH1A1EPHX2
SCHEMBL7129167 0.77 THRB (0.37) CYP19A1TSHRALDH1A1EPHX2
SCHEMBL28713506 0.76 TSHR (0.31) CYP19A1TSHR
SCHEMBL7130968 0.76 TSHR (0.45) CYP19A1TSHRALDH1A1
SCHEMBL18417858 0.76 EPHX2 (0.34) CYP19A1EPHX2
SCHEMBL13799955 0.75 TSHR (0.33) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6670499-B1 Bis-Methacryloyloxy-adamantanedicarboxylate derivatives; raw materials for dental materials and lenses; transparency, luster, hardness, water resistance DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2003-12-30 US disclosed