Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6711692 | 0.90 | KDM4E (0.51) | PDGFRBPDGFRAKDM4EALDH1A1SRD5A2 | |
| SCHEMBL6710220 | 0.89 | SRD5A2 (0.42) | SRD5A2KDM1AMAOAMAPTNPC1 | |
| SCHEMBL6919512 | 0.85 | TDP2 (0.40) | PDGFRBPDGFRASRD5A2HDAC1FLT3 | |
| SCHEMBL6713083 | 0.84 | FLT3 (0.45) | PDGFRBPDGFRAKDM4EALDH1A1SRD5A2 | |
| SCHEMBL6710127 | 0.83 | ROCK1 (0.47) | NPSR1RXFP1NPC1RAB9AROCK1 | |
| SCHEMBL6707732 | 0.82 | ROCK1 (0.41) | NPSR1RXFP1NPC1RAB9AROCK1 | |
| SCHEMBL6710169 | 0.82 | KDM4E (0.51) | PDGFRBPDGFRAKDM4EALDH1A1SRD5A2 | |
| SCHEMBL6708956 | 0.81 | LRRK2 (0.38) | MAPT | |
| SCHEMBL6709188 | 0.81 | SRD5A2 (0.42) | SRD5A2KDM1AMAOARXFP1MAPT | |
| SCHEMBL6709042 | 0.80 | KDM4E (0.48) | PDGFRBPDGFRAKDM4EALDH1A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018461-A2 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |