Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 2/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6710127 | 0.91 | ROCK1 (0.47) | ROCK1GRM4GRIK1LCKLMNA | |
| SCHEMBL6709017 | 0.91 | GRM4 (0.44) | ROCK1GRM4GRIK1LCKLMNA | |
| SCHEMBL6710227 | 0.89 | ROCK1 (0.43) | ROCK1GRM4GRIK1LCKLMNA | |
| SCHEMBL6707599 | 0.89 | TRPA1 (0.41) | ROCK1GRM4LCKLMNANSD2 | |
| SCHEMBL6708757 | 0.86 | GRIK1 (0.42) | GRIK1LMNANSD2RXFP1MEN1 | |
| SCHEMBL6713760 | 0.86 | GRIK1 (0.42) | GRIK1NSD2HIF1ANPSR1RXFP1 | |
| SCHEMBL6708679 | 0.86 | GRIK1 (0.44) | GRIK1NSD2HIF1ANPSR1RXFP1 | |
| SCHEMBL6710166 | 0.85 | NPC1 (0.43) | GRIK1LMNANPC1RAB9A | |
| SCHEMBL6713768 | 0.85 | HIF1A (0.40) | ROCK1GRM4LCKLMNAHIF1A | |
| SCHEMBL6713262 | 0.84 | GRIK1 (0.41) | GRIK1LMNANSD2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | ROCK1 4830/4885GRM4 4668/4885GRIK1 3885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.