Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6918168 | 0.80 | ALDH1A1 (1.00) | ALDH1A1MAPK1SMN1; SMN2RXFP1KMT2A | |
| SCHEMBL6819330 | 0.79 | ALDH1A1 (0.98) | ALDH1A1MAPK1SMN1; SMN2RXFP1KMT2A | |
| SCHEMBL18292476 | 0.62 | RXFP1 (1.00) | ALDH1A1MAPK1RXFP1HTTHSD17B10 | |
| SCHEMBL4789817 | 0.62 | GRIA4 (0.54) | ALDH1A1MAPK1KMT2ATSHR | |
| SCHEMBL13772455 | 0.60 | HSD17B10 (0.60) | ALDH1A1MAPK1SMN1; SMN2KMT2AHDAC6 | |
| SCHEMBL21378233 | 0.58 | KMT2A (0.44) | ALDH1A1MAPK1SMN1; SMN2KMT2AHTT | |
| SCHEMBL21056714 | 0.57 | ALDH1A1 (0.42) | ALDH1A1MAPK1KMT2AHDAC6ABCC1 | |
| SCHEMBL21869103 | 0.57 | ALDH1A1 (0.37) | ALDH1A1MAPK1HTTHSD17B10 | |
| SCHEMBL10509477 | 0.55 | LMNA (0.33) | ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL14537942 | 0.55 | LMNA (0.33) | ALDH1A1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030096813-A1 | Compositions useful as inhibitors of GSK-3 | CAO JINGRONG (US) | 2003-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030096813-A1 | Compositions useful as inhibitors of GSK-3 | GSK3B, GSK3A, GSKIP | ALDH1A1 3164/4885MAPK1 130/4885SMN1; SMN2 745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.