Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Methylbenzoic Acid SCHEMBL7126317 | 0.88 | ALDH1A1 (0.61) | MAPTALDH1A1SRD5A2KMT2AMEN1 | |
| SCHEMBL28180708 | 0.80 | KMT2A (0.56) | MAPTALDH1A1SRD5A2KMT2AMEN1 | |
| SCHEMBL6653763 | 0.79 | KMT2A (0.71) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL13932521 | 0.79 | KMT2A (0.71) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| Aes-103 SCHEMBL16684591 | 0.79 | ALDH1A1 (0.50) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL380997 | 0.78 | KMT2A (0.71) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL31268615 | 0.78 | KMT2A (0.71) | MAPTALDH1A1KMT2AMEN1HPGD | |
| 4-Methylbenzoic Acid SCHEMBL11280739 | 0.78 | ALDH1A1 (0.79) | MAPTALDH1A1SRD5A2KMT2AMEN1 | |
| Terephthalic Acid SCHEMBL6473290 | 0.78 | ALDH1A1 (0.71) | MAPTALDH1A1SRD5A2KMT2AMEN1 | |
| Terephthalic Acid SCHEMBL11366672 | 0.78 | ALDH1A1 (0.79) | MAPTALDH1A1SRD5A2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030073206-A1 | Use of xylene monooxygenase for the oxidation of substituted monocyclic aromatic compounds | E. I. DU PONT DE NEMOURS AND COMPANY | 2003-04-17 | — | — | US | disclosed |