SCHEMBL7126327

SCHEMBL7126327

O=C1OC(=O)C(C=Cc2ccccc2)C1O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.40
MAPT P10636 4/20 0.40
HTT P42858 2/20 0.40
RAB9A P51151 2/20 0.40
MEN1 O00255 1/20 0.40
JAK2 O60674 1/20 0.40
KMT2A Q03164 1/20 0.40
NFKB1 P19838 1/20 0.40
NFKB2 Q00653 1/20 0.40
RELA Q04206 1/20 0.40
ALDH1A1 P00352 4/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
CYP1A2 P05177 2/20 0.37
HDAC3 O15379 1/20 0.37
TNKS O95271 1/20 0.37
HDAC4 P56524 1/20 0.37
HDAC1 Q13547 1/20 0.37
HCAR2 Q8TDS4 1/20 0.37
HDAC7 Q8WUI4 1/20 0.37
HDAC2 Q92769 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28804659 0.75 PTGER3 (0.40)
SCHEMBL9034203 0.71 LMNA (0.39) LMNAMAPTHTTRAB9AMEN1
SCHEMBL28754688 0.70 ALDH1A1 (0.36) MAPTRAB9AMEN1KMT2AALDH1A1
SCHEMBL13075286 0.69 KDM1A (0.53) LMNAMAPTHTTRAB9AMEN1
SCHEMBL13038557 0.69 KDM1A (0.53) LMNAMAPTHTTRAB9AMEN1
SCHEMBL13346970 0.69 KDM1A (0.53) LMNAMAPTHTTRAB9AMEN1
SCHEMBL5963253 0.67 MAPT (0.42) LMNAMAPTHTTRAB9AMEN1
SCHEMBL5963254 0.67 MAPT (0.42) LMNAMAPTHTTRAB9AMEN1
SCHEMBL4726695 0.66 LMNA (0.43) LMNAMAPTHTTRAB9AMEN1
SCHEMBL24188717 0.65 KDM1A (0.44) LMNAMAPTHTTRAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3749722-B1 SMEAR RESISTANT INK COMPOSITION SUN CHEMICAL CORP (US) 2023-01-25 EP disclosed
US-6632588-B2 Film of thermo-resist applied to a substrate surface is scanned by a focused heat source without a phototool CITIBANK, N.A. 2003-10-14 US disclosed
US-20030003406-A1 Film of thermo-resist applied to a substrate surface is scanned by a focused heat source without a phototool MACDERMID, INC. 2003-01-02 US disclosed