Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.46 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 4/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MBNL1 | Q9NR56 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29177963 | 0.88 | ESR1 (0.46) | ALDH1A1HPGDKDM4EKMT2AGLA | |
| SCHEMBL29664474 | 0.84 | ESR1 (0.58) | ALDH1A1HPGDKDM4EKMT2AGLA | |
| SCHEMBL29177936 | 0.82 | ALDH1A1 (0.48) | ALDH1A1HPGDKDM4EKMT2AGLA | |
| SCHEMBL29664592 | 0.81 | ALDH1A1 (0.49) | ALDH1A1HPGDKDM4EKMT2AGLA | |
| SCHEMBL10010909 | 0.81 | ALDH1A1 (0.49) | ALDH1A1HPGDKDM4EKMT2AGLA | |
| SCHEMBL28229302 | 0.79 | ALDH1A1 (0.53) | ALDH1A1HPGDKDM4EKMT2AGLA | |
| SCHEMBL31012431 | 0.79 | ALDH1A1 (0.42) | ALDH1A1HPGDKDM4EKMT2AGLA | |
| SCHEMBL3908670 | 0.79 | NQO2 (0.47) | ALDH1A1HPGDKDM4EKMT2AGLA | |
| SCHEMBL30527881 | 0.79 | ALDH1A1 (0.52) | ALDH1A1HPGDKDM4EKMT2AGLA | |
| SCHEMBL9755342 | 0.79 | ALDH1A1 (0.52) | ALDH1A1HPGDKDM4EKMT2AGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6627659-B1 | Methods of decreasing the effects of oxidative stress using N-acetylcysteine | ZAMBON GROUP S.P.A. (IT) | 2003-09-30 | — | — | US | disclosed |
| US-20030139472-A1 | Use of N-acetylcysteine for the preparation of a medicament suitable for the intravenous administration to prevent oxidative stress in dialysed patients | ZAMBON GROUP S.P.A. (IT) | 2003-07-24 | — | — | US | disclosed |
| EP-1171112-A2 | USE OF N-ACETYLCYSTEINE FOR THE PREPARATION OF A MEDICAMENT SUITABLE FOR THE INTRAVENOUS ADMINISTRATION TO PREVENT OXIDATIVE STRESS IN DIALYSED PATIENTS | ZAMBON GROUP S.p.A. (IT) | 2002-01-16 | — | — | EP | disclosed |
| WO-2000064421-A2 | USE OF N-ACETYLCYSTEINE FOR THE PREPARATION OF A MEDICAMENT SUITABLE FOR THE INTRAVENOUS ADMINISTRATION TO PREVENT OXIDATIVE STRESS IN DIALYSED PATIENTS | ZAMBON GROUP S.P.A. (IT) | 2000-11-02 | — | — | WO | disclosed |